Dosage & Administration Drug label Prior authorization Financial assistance

Invokamet

(canagliflozin / metformin)

Invokamet 50 MG / 1000 MG Oral TabletInvokamet 50 MG / 500 MG Oral Tablet

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Dosage & administration

* Individualize starting dose based on the patient's current regimen and renal function ( 2.2, 2.3, 2.4)
* Initiation of INVOKAMET or INVOKAMET XR is not recommended in patients with an eGFR less than 45 mL/min/1.73 m 2, due to the metformin component ( 2.4)
* INVOKAMET: one tablet, twice daily with meals, recommended starting dose of canagliflozin is 50 mg twice daily and metformin HCl 500 mg twice daily ( 2.2)
* INVOKAMET XR: two tablets, once daily with the morning meal. Swallow whole. Never crush, cut, or chew ( 2.2)
* Canagliflozin dose can be increased to a total daily dose of 300 mg in patients tolerating 100 mg who have an eGFR of 60 mL/min/1.73 m 2or greater and require additional glycemic control. Do not exceed a total daily canagliflozin dose of 300 mg ( 2.2)
* Gradually escalate metformin HCl dose to reduce the gastrointestinal side effects while not exceeding a total daily dose of 2,000 mg ( 2.3)
* Assess renal function before initiating and as clinically indicated ( 2.1, 2.3)
* Dose adjustment for patients with renal impairment may be required ( 2.4)
* See full prescribing information for INVOKAMET and INVOKAMET XR dosage modifications due to drug interactions. ( 2.5)
* May need to be discontinued at time of, or prior to, iodinated contrast imaging procedures ( 2.6)
* Withhold INVOKAMET or INVOKAMET XR at least 3 days, if possible, prior to major surgery or procedures associated with prolonged fasting ( 2.7).

drug label

Invokamet prescribing information

Contact Medical Science Liaison Report Adverse Event

prior authorization

Invokamet prior authorization resources

PDFComplete Letter of Medical Necessity

PDFAppeals Considerations Checklist

PDFAppeals Considerations Checklist - Spanish

PDFFormulary Exception Request Letter

PDFFormulary Exception Request Letter - Spanish

PDFPA Checklist

PDFPA Checklist - Spanish

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Benefits investigation

PDFBenefits Investigation Form

PDFJanssen Patient Support Program Patient Authorization Form

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financial assistance

Invokamet financial assistance options

Co-pay savings program

commercial only

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Foundation programs

under insured

no insurance

goverment insurance

65+

J & J Patient Assistance Foundation Eligibility Check

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Invokamet patient education

Getting started on Invokamet

To share resource; ask patient to:

1.Pull out phone

2.Open camera

3.Scan QR code with camera

4.Tap link

Patient toolkit

BRAND PAGEAbout Invokamet XR

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Learn More

Other resources

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Invokamet FAQs

How is the dosage of Invokamet?Invokamet is available in 8 dosages, including 150-1,000 mg 24 HR XR Tab, 150-1,000 mg Tab, 150-500 mg 24 HR XR Tab, 150-500 mg Tab, 50-1,000 mg 24 HR XR Tab, 50-1,000 mg Tab, 50-500 mg 24 HR XR Tab and 50-500 mg Tab

What does Invokamet treat?Invokamet treats Type 2 Diabetes Mellitus

What is Invokamet made of?Invokamet contains canagliflozin / metformin which is a Biguanide

How Is Invokamet Administered?Invokamet is administered as a Oral Pill

FAQ Data Source

Invokamet

Dosage & administration

drug label

Invokamet prescribing information

prior authorization

Invokamet prior authorization resources

Benefits investigation

financial assistance

Invokamet financial assistance options

Co-pay savings program

Foundation programs

patient education

Invokamet patient education

Getting started on Invokamet

Patient toolkit

Other resources

people also ask

Invokamet FAQs