What is the dosage of Jakafi?

Jakafi is available in 5 dosages, including 5 mg Tab, 20 mg Tab, 15 mg Tab, 25 mg Tab and 10 mg Tab

What does Jakafi treat?

Jakafi treats Polycythemia Vera and Primary Myelofibrosis

What is Jakafi made of?

Jakafi contains ruxolitinib which is a Kinase Inhibitor

How is Jakafi administered?

Jakafi is administered as a Oral Pill

What is Jakafi mechanism of action?

Jakafi mechanism of action is Janus Kinase Inhibitors

Jakafi Prescribing & Dosing Schedule

Last Update: Oct, 21 2024

Jakafi (ruxolitinib)

Jakafi 5 MG Oral Tablet

NO BOXED WARNING

Dosage & Administration

Doses should be individualized based on safety and efficacy. Starting doses per indication are noted below.

Myelofibrosis

* The starting dose of Jakafi is based on patient’s baseline platelet count:
   •  Greater than 200 x 109/L: 20 mg given orally twice daily
   •  100 x 109/L to 200 x 109/L: 15 mg given orally twice daily
   •  50 x 109/L to less than 100 x 109/L: 5 mg given orally twice daily
* Monitor complete blood counts every 2 to 4 weeks until doses are stabilized, and then as clinically indicated. Modify or interrupt dosing for thrombocytopenia.

Polycythemia Vera

* The starting dose of Jakafi is 10 mg given orally twice daily.

Acute Graft-Versus-Host Disease

The starting dose of Jakafi is 5 mg given orally twice daily.

Chronic Graft-Versus-Host Disease

* The starting dose of Jakafi is 10 mg given orally twice daily.

Get Your Patient on Jakafi

See your patient's specific prior authorization requirements including coverage restrictions and step therapies

Or select your Insurance from the list below:

Jakafi Prescribing Information

Contact Medical Science Liaison

Report Adverse Event

Jakafi Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Sep 24, 2024Arizona - Uniform Prior Authorization Form

Verified: Sep 24, 2024Colorado - Uniform Prior Authorization Form

Verified: Sep 24, 2024Hawaii - Uniform Prior Authorization Form

Verified: Sep 24, 2024Illinois - Uniform Prior Authorization Form

Verified: Sep 24, 2024Indiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Louisiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Minnesota - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Mexico - Uniform Prior Authorization Form

Verified: Sep 24, 2024Oregon - Uniform Prior Authorization Form

Verified: Sep 24, 2024Texas - Uniform Prior Authorization Form

Verified: Oct 05, 2024Washington - Uniform Prior Authorization Form

Verified: Oct 05, 2024Wisconsin - Uniform Prior Authorization Form

Coverage Authorization Appeals

Complete Letter of Medical Necessity

Benefits investigation

IncyteCARES for Jakafi Program Enrollment Form

IncyteCARES for Jakafi Program Enrollment Form - Online

Patient Authorization for the IncyteCARES for Jakafi Program - Online

Reimbursement help (FRM)

Receive Assistance from an FRM Regarding Reimbursement Information

Jakafi Financial Assistance Options

Copay savings program

IncyteCARES for Jakafi Program Enrollment Form

Patient Authorization for the IncyteCARES for Jakafi Program - Online

IncyteCARES for Jakafi Program Enrollment Form - Online

Enroll in Patient Savings Program - HCP Office

Enroll in Patient Savings Program - Patient

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

IncyteCARES for Jakafi Program Enrollment Form

Patient Authorization for the IncyteCARES for Jakafi Program - Online

IncyteCARES for Jakafi Program Enrollment Form - Online

IncyteCARES for Jakafi Temporary Access Program - 30 Day Supply

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

IncyteCARES for Jakafi Program Enrollment Form

Patient Authorization for the IncyteCARES for Jakafi Program - Online

IncyteCARES for Jakafi Program Enrollment Form - Online

IncyteCARES for Jakafi Patient Assistance Program (PAP)

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and copays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.