Doses should be individualized based on safety and efficacy. Starting doses per indication are noted below.
Myelofibrosis
Polycythemia Vera
* The starting dose of Jakafi is 10 mg given orally twice daily.
Acute Graft-Versus-Host Disease
*
The starting dose of Jakafi is 5 mg given orally twice daily.
Chronic Graft-Versus-Host Disease
* The starting dose of Jakafi is 10 mg given orally twice daily.
eficacy, safety & testing
Jakafi clinical details
Mechanism of Action (MOA): Polycythemia Vera (PV)
Efficacy: Polycythemia Vera (PV)
Safety Profile: Polycythemia Vera (PV)
Dosing: Polycythemia Vera (PV)
Mechanism of Action (MOA): Myelofibrosis (MF)
Efficacy: Myelofibrosis (MF)
Safety Profile: Myelofibrosis (MF)
Dosing: Myelofibrosis (MF)
Mechanism of Action (MOA): Acute GVHD
Efficacy: Acute GVHD
Safety Profile: Acute GVHD
Dosing: Acute GVHD
Mechanism of Action (MOA): Chronic GVHD
Efficacy: Chronic GVHD
Safety Profile: Chronic GVHD
Dosing: Chronic GVHD
drug label
Jakafi prescribing information
Have more Jakafi questions?
Submit MSL Request
Learn More
Your request will be referred to the appropriate Incyte Corporation medical professional, such as a Jakafi pharmaceutical rep; Medical Science Liaison (MSL) or medical affairs.
Need to report a Jakafi issue?
ONLINE FORMReport adverse event
Learn More
You can report a Jakafi adverse event on MedWatch, the FDA's medical product safety reporting program for health professionals, patients and consumers.
prior authorization
Jakafi Prior authorization resources
Complete Letter of Medical Necessity
NOT PROVIDED BY BRANDCoverage Authorization Request
Coverage Authorization Appeals
Learn More
If available, these templates are provided by the brand to help you navigate insurance, especially with newer drugs.
Benefits investigation
IncyteCARES for Jakafi Program Enrollment Form
Patient Authorization for the IncyteCARES for Jakafi Program - Online
IncyteCARES for Jakafi Program Enrollment Form - Online
Learn More
Benefits investigations are conducted to determine whether a therapy is covered under a patient's insurance, if a prior authorization is required, and which specialty pharmacies are preferred.
Reimbursement help (FRM)
Receive Assistance from an FRM Regarding Reimbursement Information
Learn More
Some brands offer a field reimbursement manager who will work with your clinical staff and preferred pharmacy to help make sure patients don't fall through the cracks.
financial assistance
Jakafi Financial assistance options
Co-pay savings program
commercial only
IncyteCARES for Jakafi Program Enrollment Form
Patient Authorization for the IncyteCARES for Jakafi Program - Online
IncyteCARES for Jakafi Program Enrollment Form - Online
Enroll in Patient Savings Program - HCP Office
Enroll in Patient Savings Program - Patient
Learn More
Overview
Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)
Patient benefit
A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max
Patient eligibility
Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance
How to sign up
Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form
Bridge program
commercial only
IncyteCARES for Jakafi Program Enrollment Form
Patient Authorization for the IncyteCARES for Jakafi Program - Online
IncyteCARES for Jakafi Program Enrollment Form - Online
IncyteCARES for Jakafi Temporary Access Program - 30 Day Supply
Learn More
Overview
Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)
Patient benefit
100% free (outside of insurance)
Patient eligibility
HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries
How to sign up
Typically HCP assisted enrollment (via form)
Foundation programs
under insured
no insurance
goverment insurance
65+
IncyteCARES for Jakafi Program Enrollment Form
Patient Authorization for the IncyteCARES for Jakafi Program - Online
IncyteCARES for Jakafi Program Enrollment Form - Online
IncyteCARES for Jakafi Patient Assistance Program (PAP)
Learn More
Overview
Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned
Patient benefit
Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted
Patient eligibility
Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.
How to sign up
Patients submit proof of out-of-pocket drug costs to charities for reimbursement
patient education
Jakafi Patient education
Getting started on Jakafi
NOT PROVIDED BY BRANDInstructions For Use: Polycythemia Vera (PV)
NOT PROVIDED BY BRANDInstructions For Use: Myelofibrosis (MF)
NOT PROVIDED BY BRANDInstructions For Use: Acute GVHD
NOT PROVIDED BY BRANDInstructions For Use: Chronic GVHD
Patient toolkit
About Jakafi: Polycythemia Vera (PV)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
View How to Take Jakafi: Polycythemia Vera (PV)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Side Effects: Polycythemia Vera (PV)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Resources: Polycythemia Vera (PV)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Stories: Polycythemia Vera (PV)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Understanding Polycythemia Vera
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Understanding Polycythemia Vera - Spanish
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Polycythemia Vera, Spleen Size & You
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
PV Healthcare Appointment Workbook
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
About Jakafi: Myelofibrosis (MF)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
View How to Take Jakafi: Myelofibrosis (MF)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Side Effects: Myelofibrosis (MF)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Resources: Myelofibrosis (MF)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Stories: Myelofibrosis (MF)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Understanding Myelofibrosis
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Understanding Myelofibrosis - Spanish
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Myelofibrosis, Spleen Size &You
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
MF Healthcare Appointment Workbook
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
MPN Symptom Assessment Form (MPN SAF): Myelofibrosis (MF) & Polycythemia Vera (PV)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
About Jakafi: Acute GVHD
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
View How to Take Jakafi: Acute GVHD
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Resources: Acute GVHD
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link