Kinase Inhibitor

Janus Kinase Inhibitors

Janus Kinase Inhibitor

Polycythemia Vera

Primary Myelofibrosis

<section class="Section" data-sectioncode="34089-3"><a name="LINK_c3e16042-df70-4a0b-9bc8-6ddb2d4fbc03"></a><a name="section-10"></a><p></p><h1>11. DESCRIPTION</h1><p class="First">Ruxolitinib phosphate is a kinase inhibitor with the chemical name (<span class="Italics">R</span>)-3-(4-(7<span class="Italics">H</span>-pyrrolo[2,3-<span class="Italics">d</span>]pyrimidin-4-yl)-1<span class="Italics">H</span>-pyrazol-1-yl)-3-cyclopentylpropanenitrile phosphate and a molecular weight of 404.36. Ruxolitinib phosphate has the following structural formula:</p><p> <img alt="Ruxolitinib phosphate structure" src="jakafi-1.jpg"/></p><p>Ruxolitinib phosphate is a white to off-white to light pink powder and is soluble in aqueous buffers across a pH range of 1 to 8. </p><p>Jakafi (ruxolitinib) Tablets are for oral administration. Each tablet contains 6.6 mg, 13.2 mg, 19.8 mg, 26.4 mg, or 33 mg of ruxolitinib phosphate equivalent to 5 mg, 10 mg, 15 mg, 20 mg, or 25 mg of ruxolitinib free base, respectively, together with microcrystalline cellulose, lactose monohydrate, magnesium stearate, colloidal silicon dioxide, sodium starch glycolate, povidone and hydroxypropyl cellulose.</p></section>

JAKAFI

ruxolitinib

ruxolitinib 10 MG Oral Tablet

Jakafi

ruxolitinib 10 MG Oral Tablet [Jakafi]

ruxolitinib 5 MG Oral Tablet

ruxolitinib 5 MG Oral Tablet [Jakafi]

ruxolitinib 15 MG Oral Tablet

ruxolitinib 15 MG Oral Tablet [Jakafi]

ruxolitinib 20 MG Oral Tablet

ruxolitinib 20 MG Oral Tablet [Jakafi]

ruxolitinib 25 MG Oral Tablet

ruxolitinib 25 MG Oral Tablet [Jakafi]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information

Medication Guide 

Submit MSL Request 

Pharmacy List 

Billing & Coding Guide 

Reimbursement Information

Coverage Authorization Request 

Coverage Authorization Appeals 

Letter of Medical Necessity 

IncyteCARES for Jakafi Program Enrollment Form

Patient Authorization for the IncyteCARES for Jakafi Program - Online 

IncyteCARES for Jakafi Program Enrollment Form - Online

Enroll in Patient Savings Program - HCP Office 

Enroll in Patient Savings Program - Patient 

IncyteCARES for Jakafi Patient Assistance Program (PAP)

IncyteCARES for Jakafi Temporary Access Program - 30 Day Supply 

Other HCP Resources: Polycythemia Vera (PV)

About Jakafi: Polycythemia Vera (PV)

Taking Jakafi: Polycythemia Vera (PV)

Side Effects: Polycythemia Vera (PV)

Patient Resources: Polycythemia Vera (PV)

Patient Stories: Polycythemia Vera (PV)

Understanding Polycythemia Vera

Instructions For Use: Polycythemia Vera (PV)

Understanding Polycythemia Vera - Spanish 

Polycythemia Vera, Spleen Size & You

PV Healthcare Appointment Workbook

Other HCP Resources: Myelofibrosis (MF)

About Jakafi: Myelofibrosis (MF)

Taking Jakafi: Myelofibrosis (MF)

Side Effects: Myelofibrosis (MF)

Patient Resources: Myelofibrosis (MF)

Patient Stories: Myelofibrosis (MF)

Instructions For Use: Myelofibrosis (MF)

Understanding Myelofibrosis

Understanding Myelofibrosis - Spanish 

Myelofibrosis, Spleen Size &You

MF Healthcare Appointment Workbook

MPN Symptom Assessment Form (MPN SAF): Myelofibrosis (MF) & Polycythemia Vera (PV)

Getting Started With Jakafi: Myelofibrosis (MF) & Polycythemia Vera (PV)

Getting Started With Jakafi (Spanish): Myelofibrosis (MF) & Polycythemia Vera (PV)