Dosage & Administration Efficacy safety testing Drug label Prior authorization Financial assistance

Jevtana

(cabazitaxel)

1.5 ML cabazitaxel 40 MG/ML Injection [Jevtana]

Dosage & administration

Recommended Dose: JEVTANA 20 mg/m2 administered every three weeks as a one-hour intravenous infusion in combination with oral prednisone 10 mg administered daily throughout JEVTANA treatment.

A dose of 25 mg/m2 can be used in select patients at the discretion of the treating healthcare provider.

* JEVTANA requires two dilutions prior to administration.
* Use the entire contents of the accompanying diluent to achieve a concentration of 10 mg/mL JEVTANA.
* PVC equipment should not be used.
* Premedication Regimen: Administer intravenously 30 minutes before each dose of JEVTANA:
* Antihistamine (dexchlorpheniramine 5 mg or diphenhydramine 25 mg or equivalent antihistamine)
* Corticosteroid (dexamethasone 8 mg or equivalent steroid)
* H2 antagonist
Antiemetic prophylaxis (oral or intravenous) is recommended as needed.
* Dosage Modifications: See full prescribing information

eficacy, safety & testing

Jevtana clinical details

Mechanism of Action (MOA)

Clinical Trials: CARD

Clinical Trials: TROPIC

Clinical Trials: PROSELICA

Efficacy & Safety Profile: CARD Trial

Efficacy & Safety Profile: TROPIC Trial

Efficacy & Safety Profile: PROSELICA Trial

Dosing

Preparation & Administration

Duration of Therapy

drug label

Jevtana prescribing information

Have more Jevtana questions?

Submit MSL Request

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Need to report a Jevtana issue?

ONLINE FORMReport adverse event

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prior authorization

Jevtana Prior authorization resources

Complete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

Coverage Authorization Appeals

Letter of Medical Exception

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Benefits investigation

CareAssist Enrollment Form

CareAssist Enrollment Form - Spanish

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Reimbursement help (FRM)

Receive Assistance from an FRM Regarding Reimbursement Information

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financial assistance

Jevtana Financial assistance options

Co-pay savings program

commercial only

CareAssist Enrollment Form

CareAssist Enrollment Form - Spanish

Enroll in Patient Savings Program

Reimbursement Request (For Out of Pocket Claims)

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

CareAssist Enrollment Form

CareAssist Enrollment Form - Spanish

CareAssist Patient Assistance Program

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Jevtana Patient education