Cytochrome P450 3A Inhibitors

Kinase Inhibitor

Kinase Inhibitors

Breast Neoplasms

<section class="Section" data-sectioncode="34089-3"><a name="section-10"></a><h1>11     DESCRIPTION</h1>KISQALI (ribociclib) is a kinase inhibitor.The chemical name of ribociclib succinate is: Butanedioic acid—7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl) pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide (1/1).Ribociclib succinate is a light yellow to yellowish brown crystalline powder. The molecular formula for ribociclib succinate is C23H30N8O·C4H6O4 and the molecular weight is 552.64 g/mol (Free base: 434.55 g/mol). The chemical structure of ribociclib is shown below:<img alt="The Following chemical structure of KISQALI film-coated tablets are supplied for oral administration and contain 200 mg of ribociclib free base (equivalent to 254.40 mg ribociclib succinate). The tablets also contain colloidal silicon dioxide, crospovidone, hydroxypropylcellulose, magnesium stearate and microcrystalline cellulose. The film-coating contains iron oxide black, iron oxide red, lecithin (soya), polyvinyl alcohol (partially hydrolysed), talc, titanium dioxide, and xanthan gum as inactive ingredients. " src="kisqali-01.jpg"/>KISQALI film-coated tablets are supplied for oral use and contain 200 mg of ribociclib free base (equivalent to 254.40 mg ribociclib succinate). The tablets also contain colloidal silicon dioxide, crospovidone, hydroxypropylcellulose, magnesium stearate and microcrystalline cellulose. The film-coating contains iron oxide black, iron oxide red, lecithin (soya), polyvinyl alcohol (partially hydrolysed), talc, titanium dioxide, and xanthan gum as inactive ingredients.</section>

KISQALI

Kisqali

ribociclib

ribociclib 200 MG Oral Tablet

ribociclib 200 MG Oral Tablet [Kisqali]

Cooks Children Home Health

Actemra

Afinitor

Alecensa

Alunbrig

Aranesp

Ayvakit

Benlysta

Bosulif

Braftovi

Brukinsa

Cabometyx

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Copiktra

Cosentyx

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Daurismo

Enbrel

Entyvio

Erivedge

Erleada

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Fasenra

Hemlibra

Ibrance

Ilumya

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Inlyta

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Inrebic

Iressa

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Tykerb

Tymlos

Venclexta

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Xalkori

Xolair

Xtandi

Yonsa

Zelboraf

Zeposia

Zydelig

Kisqali | Cooks Children Home Health

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