Insulin Analog

Type 1 Diabetes Mellitus

Type 2 Diabetes Mellitus

Hyperglycemia

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Insulin glargine is a long-acting human insulin analog produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of <span class="Italics">Escherichia coli</span> (K12). Insulin glargine differs from human insulin in that the amino acid asparagine at position A21 is replaced by glycine and two arginines are added to the C-terminus of the B-chain. Insulin glargine has a molecular weight of 6063 Da. </p><p>LANTUS (insulin glargine) injection is a sterile, clear and colorless solution for subcutaneous use in a 10 mL multiple-dose vial or a 3 mL single-patient use prefilled pen (LANTUS Solostar).</p><p>Prefilled Pen (LANTUS Solostar) and Vial: Each mL contains 100 units of insulin glargine and the inactive ingredients: glycerol 85% (20 mg), m-cresol (2.7 mg), zinc (30 mcg), and Water for Injection, USP. The vial also contains polysorbate 20 (20 mcg). The pH is adjusted by addition of aqueous solutions of hydrochloric acid and sodium hydroxide. LANTUS has a pH of approximately 4.</p></section>

Lantus

3 ML insulin glargine 100 UNT/ML Pen Injector

3 ML insulin glargine 100 UNT/ML Pen Injector [Lantus]

insulin glargine

insulin glargine 100 UNT/ML Injectable Solution

insulin glargine 100 UNT/ML Injectable Solution [Lantus]

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