Amyloid Beta-directed Antibody Interactions

Amyloid Beta-directed Antibody

Alzheimer Disease

<section class="Section" data-sectioncode="34089-3"><a name="_11_DESCRIPTION"></a><a name="section-8"></a><p></p><h1><span class="Bold">11</span>        <span class="Bold">DESCRIPTION </span></h1><p class="First">Lecanemab-irmb is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta, and is expressed in a Chinese hamster ovary cell line. Lecanemab-irmb has an approximate molecular weight of 150 kDa.</p><p>LEQEMBI (lecanemab-irmb) injection is a preservative-free, sterile, clear to opalescent and colorless to pale yellow solution for intravenous use by infusion after dilution. LEQEMBI is supplied in single-dose vials available in concentrations of 500 mg/5 mL (100 mg/mL) or 200 mg/2 mL (100 mg/mL). </p><p>Each mL of solution contains 100 mg of lecanemab-irmb and arginine hydrochloride (42.13 mg), histidine (0.18 mg), histidine hydrochloride monohydrate (4.99 mg), polysorbate 80 (0.50 mg), and Water for Injection at an approximate pH of 5.0.</p></section>

LEQEMBI

lecanemab-irmb

lecanemab

2 ML lecanemab-irmb 100 MG/ML Injection

Leqembi

2 ML lecanemab-irmb 100 MG/ML Injection [Leqembi]

5 ML lecanemab-irmb 100 MG/ML Injection

5 ML lecanemab-irmb 100 MG/ML Injection [Leqembi]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event

Prescribing Information

Medication Guide 

Submit MSL Request 

Pharmacy List 

How To Order Leqembi

Billing & Coding Guide 

Coverage Authorization Request 

Coverage Authorization Appeals 

Letter of Medical Necessity 

Request for Prescription Drug Coverage Exception Letter 

Leqembi Eisai Patient Support Program Enrollment Form

Enroll in Patient Savings Program 

Other HCP Resources 

About Leqembi

Side Effects

Receiving Leqembi Infusion

Patient Resources 

Leqembi Companion

Patient Brochure

Appointment Tracker

Your Guide To Leqembi Infusions

Instructions For Use: Alzheimer's 