Lyrica
(Pregabalin)Dosage & Administration
INDICATION | Dosing Regimen | Maximum Dose |
|---|---|---|
DPN Pain | 3 divided doses per day | 300 mg/day within 1 week |
PHN | 2 or 3 divided doses per day | 300 mg/day within 1 week. |
Adjunctive Therapy for Partial-Onset Seizures in Pediatric and Adult Patients Weighing 30 kg or More | 2 or 3 divided doses per day | Maximum dose of 600 mg/day. |
Adjunctive Therapy for Partial-Onset Seizures in Pediatric Patients Weighing Less than 30 kg | 1 month to less than 4 years: 3 divided doses per day 4 years and older: 2 or 3 divided doses per day | 14 mg/kg/day. |
Fibromyalgia | 2 divided doses per day | 300 mg/day within 1 week. |
Neuropathic Pain Associated with Spinal Cord Injury | 2 divided doses per day | 300 mg/day within 1 week. |
Lyrica Prescribing Information
Warnings and Precautions, Respiratory Depression | 4/2020 |
LYRICA is indicated for:
• Management of neuropathic pain associated with diabetic peripheral neuropathy• Management of postherpetic neuralgia• Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older• Management of fibromyalgia• Management of neuropathic pain associated with spinal cord injury
• For adult indications, begin dosing at 150 mg/day. For partial-onset seizure dosing in pediatric patients 1 month of age and older, refer to section 2.4.• Dosing recommendations:
INDICATION | Dosing Regimen | Maximum Dose |
|---|---|---|
DPN Pain | 3 divided doses per day | 300 mg/day within 1 week |
PHN | 2 or 3 divided doses per day | 300 mg/day within 1 week. |
Adjunctive Therapy for Partial-Onset Seizures in Pediatric and Adult Patients Weighing 30 kg or More | 2 or 3 divided doses per day | Maximum dose of 600 mg/day. |
Adjunctive Therapy for Partial-Onset Seizures in Pediatric Patients Weighing Less than 30 kg | 1 month to less than 4 years: 3 divided doses per day 4 years and older: 2 or 3 divided doses per day | 14 mg/kg/day. |
Fibromyalgia | 2 divided doses per day | 300 mg/day within 1 week. |
Neuropathic Pain Associated with Spinal Cord Injury | 2 divided doses per day | 300 mg/day within 1 week. |
• Dose should be adjusted in adult patients with reduced renal function.
Capsules: 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, and 300 mg
Oral Solution: 20 mg/mL
• Pregnancy: May cause fetal harm. Advise of potential risk to the fetus.• Lactation: Breastfeeding is not recommended.
LYRICA is contraindicated in patients with known hypersensitivity to pregabalin or any of its components. Angioedema and hypersensitivity reactions have occurred in patients receiving pregabalin therapy