What is the dosage of Nerlynx?

Nerlynx is available in 1 dosages, including 40 mg Tab

What does Nerlynx treat?

Nerlynx treats Breast Neoplasms

What is Nerlynx made of?

Nerlynx contains neratinib which is a Kinase Inhibitor

How is Nerlynx administered?

Nerlynx is administered as a Oral Pill

What is Nerlynx mechanism of action?

Nerlynx mechanism of action is Kinase Inhibitors or P-Glycoprotein Inhibitors

Dosage & Administration Drug label Samples Prior authorization Financial assistance

Patient education

Nerlynx

(neratinib)

neratinib 40 MG Oral Tablet [Nerlynx]

NO BLACK BOX WARNING

Dosage & administration

* Premedication for diarrhea: When not using dose escalation, initiate loperamide with the first dose of NERLYNX and continue during the first 56 days of treatment. After day 56, use loperamide to maintain 1–2 bowel movements per day. ( 2.1, 2.2)
* Extended adjuvant treatment of early-stage breast cancer: 240 mg (6 tablets) given orally once daily, with food, continuously until disease recurrence for up to one year. ( 2.2)
* Advanced or metastatic breast cancer: 240 mg (6 tablets) given orally once daily with food on Days 1–21 of a 21-day cycle plus capecitabine (750 mg/m 2 given orally twice daily) on Days 1–14 of a 21-day cycle until disease progression or unacceptable toxicities. ( 2.2)
* Dose escalation: A two-week dose escalation for NERLYNX may also be initiated. ( 2.2)
* Dose interruptions and/or dose reductions are recommended based on individual safety and tolerability. ( 2.3)
* Hepatic impairment: Reduce starting dose to 80 mg in patients with severe hepatic impairment. ( 2.4)

drug label

Nerlynx prescribing information

Have more Nerlynx questions?

Submit MSL Request

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Need to report a Nerlynx issue?

ONLINE FORMReport adverse event

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samples

Request Nerlynx samples

NOT PROVIDED BY BRANDView Online Sample Form

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prior authorization

Nerlynx Prior authorization resources

Complete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

Coverage Authorization Appeals

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Benefits investigation

Nerlynx Enrollment Form

Nerlynx Enrollment Form - Spanish

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Reimbursement help (FRM)

NOT PROVIDED BY BRANDReimbursement help (FRM) resources

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financial assistance

Nerlynx Financial assistance options

Co-pay savings program

commercial only

Nerlynx Enrollment Form

Nerlynx Enrollment Form - Spanish

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

Nerlynx Enrollment Form

Nerlynx Enrollment Form - Spanish

Nerlynx Quick Start Program

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

Nerlynx Enrollment Form

Nerlynx Enrollment Form - Spanish

Patient Assistance Program

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Nerlynx Patient education

Getting started on Nerlynx

NOT PROVIDED BY BRANDInstructions for Use: Early Stage HER2+ Breast Cancer

NOT PROVIDED BY BRANDInstructions For Use: Metastatic Breast Cancer