What is the dosage of Orladeyo?

Orladeyo is available in 2 dosages, including 110 mg Cap and 150 mg Cap

What is Orladeyo mechanism of action?

Orladeyo mechanism of action is Cytochrome P450 2D6 Inhibitors, Cytochrome P450 3A4 Inhibitors, Kallikrein Inhibitors or P-Glycoprotein Inhibitors

Orladeyo Prescribing & Dosing Schedule

Q: What is Orladeyo made of?

Orladeyo contains berotralstat which is a Plasma Kallikrein Inhibitor

Q: How is Orladeyo administered?

Orladeyo is administered as a Oral Pill

Dosage & Administration

* Recommended Dosage: One capsule (150 mg) taken orally once daily with food.

See Full Prescribing Information for:

* Dosage adjustment in patients with moderate or severe hepatic impairment.
* Dosage adjustment in patients with persistent gastrointestinal reactions.

Get Your Patient on Orladeyo

See your patient's specific prior authorization requirements including coverage restrictions and step therapies

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Orladeyo Prescribing Information

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Orladeyo Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Sep 24, 2024Arizona - Uniform Prior Authorization Form

Verified: Sep 24, 2024Colorado - Uniform Prior Authorization Form

Verified: Sep 24, 2024Hawaii - Uniform Prior Authorization Form

Verified: Sep 24, 2024Illinois - Uniform Prior Authorization Form

Verified: Sep 24, 2024Indiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Louisiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Minnesota - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Mexico - Uniform Prior Authorization Form

Verified: Sep 24, 2024Oregon - Uniform Prior Authorization Form

Verified: Sep 24, 2024Texas - Uniform Prior Authorization Form

Verified: Oct 05, 2024Washington - Uniform Prior Authorization Form

Verified: Oct 05, 2024Wisconsin - Uniform Prior Authorization Form

Benefits investigation

Orladeyo Start Form

Orladeyo Financial Assistance Options

Copay savings program

Orladeyo Start Form

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

Orladeyo Start Form

Bridge Program

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries