What is the dosage of Otrexup?

Otrexup is available in 7 dosages, including 25 mg/ml Auto-Injector 0.4 ml, 31.3 mg/ml Auto-Injector 0.4 ml, 37.5 mg/ml Auto-Injector 0.4 ml, 43.8 mg/ml Auto-Injector 0.4 ml, 50 mg/ml Auto-Injector 0.4 ml, 56.3 mg/ml Auto-Injector 0.4 ml and 62.5 mg/ml Auto-Injector 0.4 ml

What does Otrexup treat?

Otrexup treats Juvenile Arthritis, Rheumatoid Arthritis, Breast Neoplasms, Choriocarcinoma, Crohn Disease, Esophageal Neoplasms, Hydatidiform Mole, Leukemia, Lung Neoplasms, Mycosis Fungoides, Psoriasis, Osteosarcoma, Stomach Neoplasms and Testicular Neoplasms

What is Otrexup made of?

Otrexup contains methotrexate which is a Folate Analog Metabolic Inhibitor

How is Otrexup administered?

Otrexup is administered as a Injectable

What is Otrexup mechanism of action?

Otrexup mechanism of action is Folic Acid Metabolism Inhibitors

Dosage & Administration Drug label Samples Prior authorization Financial assistance

Patient education

Otrexup

(methotrexate)

0.4 ML methotrexate 25 MG/ML Auto-Injector [Otrexup]0.4 ML methotrexate 31.3 MG/ML Auto-Injector [Otrexup]

View 5 more

BLACK BOX WARNING

Dosage & administration

* Otrexup is for once weekly subcutaneous use only. Administer Otrexup in the abdomen or thigh. .
* Use another formulation of methotrexate for patients requiring oral, intramuscular, intravenous, intra-arterial, or intrathecal dosing, doses less than 10 mg per week, doses above 25 mg per week, high-dose regimens, or dose adjustments of less than 5 mg increments .
* Starting doses of methotrexate:
* RA: 7.5 mg once weekly .
* pJIA: 10 mg/m2 once weekly .
* Psoriasis: 10 to 25 mg once weekly of an oral, intramuscular, subcutaneous, or intravenous formulation .

* Adjust dose gradually to achieve an optimal response .

Otrexup prescribing information

Have more Otrexup questions?

Submit MSL Request

Learn More

Need to report an Otrexup issue?

ONLINE FORMReport adverse event

Learn More

samples

Request Otrexup samples

Online Order Form

Learn More

prior authorization

Otrexup Prior authorization resources

NOT PROVIDED BY BRANDComplete Letter of Medical Necessity

Coverage Authorization Request

NOT PROVIDED BY BRANDComplete Coverage Authorization appeals

Coverage Authorization Appeal

Learn More

Benefits investigation

NOT PROVIDED BY BRANDBenefits investigation resources

Learn More

Reimbursement help (FRM)

NOT PROVIDED BY BRANDReimbursement help (FRM) resources

Learn More

financial assistance

Otrexup Financial assistance options

Co-pay savings program

commercial only

Enroll in patient savings program

Mail -in Rebate Form ( if co-pay card not accepted)

Learn More

Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

Learn More

Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

Learn More

Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Otrexup Patient education

Getting started on Otrexup

Instructions For Use - Rheumatoid Arthritis

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Instructions For Use - Plaque Psoriasis

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Instructions For Use - Polyarticular Juvenile Idiopathic Arthritis (pJIA)

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Patient toolkit

About Otrexup

ASK PATIENT TO:
Open Camera on Phone
Scan QR Code & Tap Link

Learn More

Can't find what you're looking for?

Our trained staff can help you:

Please note:

Access to a Field Reimbursement Manager (FRM) or Medical Science Liaison (MSL) varies by brand and may require talking with your rep first.
Samples are provided at the discretion of the brand.
We are unable to collect Protected Health Information (PHI), fill out forms, or submit them on your behalf.

Otrexup

Dosage & administration

Most viewed Otrexup resources

drug label

Otrexup prescribing information

Have more Otrexup questions?

Need to report an Otrexup issue?

samples

Request Otrexup samples

Is my patient elegible for Otrexup samples?

How do I find out who my Otrexup rep is?

prior authorization

Otrexup Prior authorization resources

Benefits investigation

Reimbursement help (FRM)

financial assistance

Otrexup Financial assistance options

Co-pay savings program

Overview

Patient benefit

Patient eligibility

How to sign up

Bridge program

Overview

Patient benefit

Patient eligibility

How to sign up

Foundation programs

Overview

Patient benefit

Patient eligibility

How to sign up

patient education

Otrexup Patient education

Getting started on Otrexup

Patient toolkit

Can't find what you're looking for?