Rituxan

(rituximab)

10 ML rituximab 10 MG/ML Injection [Rituxan]50 ML rituximab 10 MG/ML Injection [Rituxan]

Dosage & administration

* Administer only as an intravenous infusion .
* Do not administer as an intravenous push or bolus .
* RITUXAN should only be administered by a healthcare professional with appropriate medical support to manage severe infusion-related reactions that can be fatal if they occur. .
* The dose for adult and pediatric B-cell NHL is 375 mg/m2 .
* The dose for CLL is 375 mg/m2 in the first cycle and 500 mg/m2 in cycles 2–6, in combination with FC, administered every 28 days .
* The dose as a component of Zevalin® (ibritumomab tiuxetan) Therapeutic Regimen is 250 mg/m2 .
* The dose for RA in combination with methotrexate is two-1,000 mg intravenous infusions separated by 2 weeks (one course) every 24 weeks or based on clinical evaluation, but not sooner than every 16 weeks. Methylprednisolone 100 mg intravenous or equivalent glucocorticoid is recommended 30 minutes prior to each infusion .
* The induction dose for adult patients with active GPA and MPA in combination with glucocorticoids is 375 mg/m2 once weekly for 4 weeks. The follow up dose for adult patients with GPA and MPA who have achieved disease control with induction treatment, in combination with glucocorticoids is two 500 mg intravenous infusions separated by two weeks, followed by a 500 mg intravenous infusion every 6 months thereafter based on clinical evaluation .
* The induction dose for pediatric patients with GPA and MPA in combination with glucocorticoids is 375 mg/m2 once weekly for 4 weeks. The follow up dose for pediatric patients with GPA and MPA who have achieved disease control with induction treatment, in combination with glucocorticoids is two 250 mg/m2 intravenous infusions separated by two weeks, followed by a 250 mg/m2 intravenous infusion every 6 months thereafter based on clinical evaluation .
* The dose for PV is two-1,000 mg intravenous infusions separated by 2 weeks in combination with a tapering course of glucocorticoids, then a 500 mg intravenous infusion at Month 12 and every 6 months thereafter or based on clinical evaluation. Dose upon relapse is a 1,000 mg intravenous infusion with considerations to resume or increase the glucocorticoid dose based on clinical evaluation. Subsequent infusions may be no sooner than 16 weeks after the previous infusion . Methylprednisolone 100 mg intravenous or equivalent glucocorticoid is recommended 30 minutes prior to each infusion .

Most viewed Rituxan resources

Coverage Authorization Appeal - Rheumatoid Arthritis (RA)

Letter of Medical Necessity - Rheumatoid Arthritis (RA)

Coverage Authorization Appeal - Granulomatosis with Polyangiitis (GPA) & Microscopic Polyangiitis (MPA) or Pemphigus Vulgaris (PV)

Letter of Medical Necessity - Granulomatosis with Polyangiitis (GPA) & Microscopic Polyangiitis (MPA) or Pemphigus Vulgaris (PV)

eficacy, safety & testing

Rituxan clinical details

drug label

Rituxan prescribing information

Have more Rituxan questions?

Submit MSL Request

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Need to report a Rituxan issue?

ONLINE FORMReport adverse event

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prior authorization

Rituxan Prior authorization resources

NOT PROVIDED BY BRANDComplete Letter of Medical Necessity

NOT PROVIDED BY BRANDCoverage Authorization Request

NOT PROVIDED BY BRANDComplete Coverage Authorization appeals

NOT PROVIDED BY BRANDCoverage Authorization Appeal - Non Hogkin's Lymphoma (NHL) & Chronic Lymphocytic Leukemia (CLL)

Coverage Authorization Appeal - Rheumatoid Arthritis (RA)

Letter of Medical Necessity - Rheumatoid Arthritis (RA)

Coverage Authorization Appeal - Granulomatosis with Polyangiitis (GPA) & Microscopic Polyangiitis (MPA) or Pemphigus Vulgaris (PV)

Letter of Medical Necessity - Granulomatosis with Polyangiitis (GPA) & Microscopic Polyangiitis (MPA) or Pemphigus Vulgaris (PV)

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Benefits investigation

NOT PROVIDED BY BRANDBenefits investigation resources

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Reimbursement help (FRM)

Reimbursement Information - Non Hodkins Lymphoma (NHL) & Chronic Lymphocytic Leukemia (CLL)

Reimbursement Information - Rheumatoid Arthritis (RA), Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA), Pemphigus Vulgaris (PV)

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financial assistance

Rituxan Financial assistance options

Co-pay savings program

commercial only

Enroll in patient savings program - Non Hogkin's Lymphoma (NHL) & Chronic Lymphocytic Leukemia (CLL)

Enroll in patients savings program - Granulomatosis with Polyangiitis (GPA) & Microscopic Polyangiitis (MPA) or Pemphigus Vulgaris (PV)

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

commercial only

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Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries

How to sign up

Typically HCP assisted enrollment (via form)

Foundation programs

under insured

no insurance

goverment insurance

65+

Genentech Patient Assistance Program Application Form (1/2 )- Patient Consent Form

Genentech Patient Assitance Program Application Form (2/2) - To be filled by Physician

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Overview

Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned

Patient benefit

Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted

Patient eligibility

Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.

How to sign up

Patients submit proof of out-of-pocket drug costs to charities for reimbursement

patient education

Rituxan Patient education

Getting started on Rituxan

NOT PROVIDED BY BRANDInstructions For Use - Non Hodkins Lymphoma (NHL)

NOT PROVIDED BY BRANDInstructions For Use - Chronic Lymphocytic Leukemia (CLL)

NOT PROVIDED BY BRANDInstructions For Use - Rheumatoid Arthritis (RA)

NOT PROVIDED BY BRANDInstructions For Use - Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA)

NOT PROVIDED BY BRANDInstructions For Use - Pemphigus Vulgaris (PV)