What is the dosage of Sympazan?

Sympazan is available in 3 dosages, including 20 mg Film, 5 mg Film and 10 mg Film

What is Sympazan mechanism of action?

Sympazan mechanism of action is Cytochrome P450 2D6 Inhibitors or Cytochrome P450 3A4 Inducers

Sympazan Prescribing & Dosing Schedule

Q: What does Sympazan treat?

Sympazan treats Seizures and Lennox Gastaut Syndrome

Q: What is Sympazan made of?

Sympazan contains clobazam which is a Benzodiazepine

Q: How is Sympazan administered?

Sympazan is administered as a Oral Film

Dosage & Administration

* For doses above 5 mg/day, administer in two divided doses

* Patients weighing 30 kg or less: Initiate at 5 mg daily, and titrate as tolerated up to 20 mg daily

* Patients weighing greater than 30 kg: Initiate at 10 mg daily, and titrate as tolerated up to 40 mg daily

* Dosage adjustment is needed in following groups:
○ Geriatric patients
○ Known CYP2C19 poor metabolizers
○ Mild or moderate hepatic impairment; no information for severe hepatic impairment

* Can be taken with or without food

* Do not administer with liquids

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Sympazan Prescribing Information

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Sympazan Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Sep 24, 2024Arizona - Uniform Prior Authorization Form

Verified: Sep 24, 2024Colorado - Uniform Prior Authorization Form

Verified: Sep 24, 2024Hawaii - Uniform Prior Authorization Form

Verified: Sep 24, 2024Illinois - Uniform Prior Authorization Form

Verified: Sep 24, 2024Indiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Louisiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Minnesota - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Mexico - Uniform Prior Authorization Form

Verified: Sep 24, 2024Oregon - Uniform Prior Authorization Form

Verified: Sep 24, 2024Texas - Uniform Prior Authorization Form

Verified: Oct 05, 2024Washington - Uniform Prior Authorization Form

Verified: Oct 05, 2024Wisconsin - Uniform Prior Authorization Form

Coverage Authorization Request

Complete Letter of Medical Necessity

Sympazan Financial Assistance Options

Copay savings program

Enroll in a Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form