Dosage & Administration Drug label People also ask

Prograf

(tacrolimus)

tacrolimus 0.5 MG Oral Capsuletacrolimus 1 MG Oral Capsule

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Dosage & administration

* Intravenous (IV) use recommended for patients who cannot tolerate oral formulations (capsules).
* Administer capsules consistently with or without food.
* Therapeutic drug monitoring is recommended.
* Avoid eating grapefruit or drinking grapefruit juice.
* See dosage adjustments for African-American patients , hepatic and renal impaired.
* For complete dosing information, see Full Prescribing Information.

ADULT
Patient Population		Initial Oral Dosage (formulation)	Whole Blood Trough Concentration Range
Kidney Transplant
With azathioprine		0.2 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1 to 3: 7 to 20 ng/mL Month 4 to 12: 5 to 15 ng/mL
With MMF/IL-2 receptor antagonist		0.1 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1 to 12: 4 to 11 ng/mL
Liver Transplant
With corticosteroids only		0.1 to 0.15 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1 to 12: 5 to 20 ng/mL
Heart Transplant
With azathioprine or MMF		0.075 mg/kg/day capsules, divided in two doses, every 12 hours	Month 1 to 3: 10 to 20 ng/mL Month ≥ 4: 5 to 15 ng/mL
PEDIATRIC
Patient Population	Initial Oral Dosage (formulation)			Whole Blood Trough Concentration Range
Liver Transplant
		0.15 to 0.2 mg/kg/day capsules divided in two doses, every 12 hours	Month 1 to 12: 5 to 20 ng/mL

MMF = Mycophenolate mofetil

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Prograf prescribing information

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Prograf FAQs

How is the dosage of Prograf?Prograf is available in 3 dosages, including 0.5 mg Cap, 1 mg Cap and 5 mg Cap

What does Prograf treat?Prograf treats Atopic Dermatitis and Graft vs Host Disease

How Is Prograf Administered?Prograf is administered as a Oral Pill

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