What is the dosage of Uplizna?

Uplizna is available in 2 dosages, including mixed Pack and 10 mg/ml Injection 10 ml

What does Uplizna treat?

Uplizna treats Neuromyelitis Optica

What is Uplizna made of?

Uplizna contains inebilizumab which is a CD19-directed Cytolytic Antibody

How is Uplizna administered?

Uplizna is administered as a Pack or Injectable

What is Uplizna mechanism of action?

Uplizna mechanism of action is CD19-directed Antibody Interactions

Uplinza Prescribing & Dosing Schedule

Dosage & Administration

* Hepatitis B virus, quantitative serum immunoglobulins, and tuberculosis screening is required before the first dose

* Prior to every infusion:
* Determine if there is an active infection

* Premedicate with a corticosteroid, an antihistamine, and an antipyretic

* UPLIZNA must be diluted in 250 mL of 0.9% Sodium Chloride Injection, USP prior to administration

* UPLIZNA is administered as an intravenous infusion titrated to completion, approximately 90 minutes. The recommended dose is:
* Initial dose: 300 mg intravenous infusion followed two weeks later by a second 300 mg intravenous infusion

* Subsequent doses (starting 6 months from the first infusion): single 300 mg intravenous infusion every 6 months

* Monitor patients closely during the infusion and for at least one hour after completion of the infusion

Get Your Patient on Uplinza

See your patient's specific prior authorization requirements including coverage restrictions and step therapies

Or select your Insurance from the list below:

Uplinza Prescribing Information

Contact Medical Science Liaison

Report Adverse Event

Uplinza Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Sep 24, 2024Arizona - Uniform Prior Authorization Form

Verified: Sep 24, 2024Colorado - Uniform Prior Authorization Form

Verified: Sep 24, 2024Hawaii - Uniform Prior Authorization Form

Verified: Sep 24, 2024Illinois - Uniform Prior Authorization Form

Verified: Sep 24, 2024Indiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Louisiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Minnesota - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Mexico - Uniform Prior Authorization Form

Verified: Sep 24, 2024Oregon - Uniform Prior Authorization Form

Verified: Sep 24, 2024Texas - Uniform Prior Authorization Form

Verified: Oct 05, 2024Washington - Uniform Prior Authorization Form

Verified: Oct 05, 2024Wisconsin - Uniform Prior Authorization Form

Appeals Checklist

Coverage Authorization Appeals

Complete Letter of Medical Necessity

PA Checklist

PA Considerations

Benefits investigation

Uplinza Patient Enrollment Form

Uplinza Patient Enrollment Form - Online

Reimbursement help (FRM)

Receive Assistance from an FRM Regarding Reimbursement Information

Uplinza Preferred Pharmacy

Pharmacy List

Uplinza Financial Assistance Options

Copay savings program

Uplinza Patient Enrollment Form

Uplinza Patient Enrollment Form - Online

Enroll in Patient Savings Program

Learn More

Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

Bridge program

Uplinza Patient Enrollment Form

Uplinza Patient Enrollment Form - Online

Starter Bridge Program

Learn More

Overview

Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)

Patient benefit

100% free (outside of insurance)

Patient eligibility

HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries