Folic Acid Metabolism Inhibitors

Folate Analog Metabolic Inhibitor

Arthritis, Juvenile

Arthritis, Rheumatoid

Breast Neoplasms

Choriocarcinoma

Crohn Disease

Esophageal Neoplasms

Hydatidiform Mole

Leukemia

Lung Neoplasms

Mycosis Fungoides

Psoriasis

Osteosarcoma

Stomach Neoplasms

Testicular Neoplasms

<section class="Section" data-sectioncode="34089-3"><a name="ID_80f19f13-77ae-4ba2-832d-65532c1c79f1"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION </h1><p class="First">XATMEP contains methotrexate, a folate analog metabolic inhibitor.</p><p>Chemically methotrexate is N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]-benzoyl]-L-glutamic acid.  The structural formula is:</p><div class="Figure"><a name="id108707299"></a><img alt="Structural Formula" src="image-01.jpg"/></div><p>XATMEP is a clear yellow to orange oral solution that contains 2.5 mg of methotrexate per milliliter (equivalent to 2.74 mg of methotrexate sodium/mL).  Inactive ingredients include purified water, sodium citrate, citric acid, methylparaben sodium, propylparaben sodium, and sucralose.  It may also contain sodium hydroxide or hydrochloric acid for pH adjustment.</p></section>

Xatmep

methotrexate 2.5 MG/ML Oral Solution

methotrexate 2.5 MG/ML Oral Solution [Xatmep]

methotrexate

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event

Prescribing Information

Pharmacy List 

How To Order Xatmep

Coverage Authorization Request

Coverage Authorization Appeals

Xatmep Patient Enrollment Form 

Xatmep Patient Assistance Program

Enroll in Patient Savings Program 

Prior Authorization Tools 

About Xatmep

FAQs: Pediatric ALL & pJIA

Patient Resources 

Instructions For Use: Pediatric ALL

Instructions For Use: pJIA