Xenazine

(tetrabenazine)

Xenazine 12.5 MG Oral TabletXenazine 25 MG Oral Tablet

Dosage & administration

* Individualization of dose with careful weekly titration is required. The 1st week’s starting dose is 12.5 mg daily; 2nd week, 25 mg (12.5 mg twice daily); then slowly titrate at weekly intervals by 12.5 mg to a tolerated dose that reduces chorea.
* Doses of 37.5 mg and up to 50 mg/day should be administered in three divided doses per day with a maximum recommended single dose not to exceed 25 mg.
* Patients requiring doses above 50 mg/day should be genotyped for the drug metabolizing enzyme CYP2D6 to determine if the patient is a poor metabolizer (PM) or an extensive metabolizer (EM).
* Maximum daily dose in EMs and intermediate metabolizers (IMs): 100 mg with a maximum single dose of 37.5 mg
* If serious adverse reactions occur, titration should be stopped and the dose should be reduced. If the adverse reaction(s) do not resolve, consider withdrawal of XENAZINE.

drug label

Xenazine prescribing information

Contact Medical Science Liaison Report Adverse Event

prior authorization

Xenazine prior authorization resources

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Benefits investigation

PDFXenazine Treatment & Prescription Form

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financial assistance

Xenazine financial assistance options

Co-pay savings program

commercial only

OTHEREnroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form

patient education

Xenazine patient education

Getting started on Xenazine

To share resource; ask patient to:

1.Pull out phone

2.Open camera

3.Scan QR code with camera

4.Tap link

Patient toolkit

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Other resources

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Xenazine FAQs

How is the dosage of Xenazine?Xenazine is available in 2 dosages, including 12.5 mg Tab and 25 mg Tab

What does Xenazine treat?Xenazine treats Huntington Disease and Hyperkinesis

What is Xenazine made of?Xenazine contains tetrabenazine which is a Vesicular Monoamine Transporter 2 Inhibitor

How Is Xenazine Administered?Xenazine is administered as a Oral Pill

What Are The Xenazine Mechanism Of Action?Xenazine mechanism of action is Vesicular Monoamine Transporter 2 Inhibitors

FAQ Data Source

Xenazine

Dosage & administration

drug label

Xenazine prescribing information

prior authorization

Xenazine prior authorization resources

Benefits investigation

financial assistance

Xenazine financial assistance options

Co-pay savings program

patient education

Xenazine patient education

Getting started on Xenazine

Patient toolkit

Other resources

people also ask

Xenazine FAQs