Xyrem

(sodium oxybate)
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Dosage & Administration

Dosage for Adult Patients

Total Nightly Dose

Take at Bedtime

Take 2.5 to 4 Hours Later

4.5 g per night

2.25 g

2.25 g

6 g per night

3 g

3 g

7.5 g per night

3.75 g

3.75 g

9 g per night

4.5 g

4.5 g


Dosage for Pediatric Patients (7 years of Age and Older)


Important Administration Information


Patients with Hepatic Impairment

Recommended starting dosage is one-half of the original dosage per night administered orally, divided into two doses .

Xyrem Prescribing Information

Xyrem Prior Authorization Resources

Most recent state uniform prior authorization forms

Reimbursement help (FRM)

Xyrem PubMed™ News

    Xyrem Patient Education

    Getting started on Xyrem

    Patient toolkit