See Full Prescribing Information for complete dosing instructions .
Dosage for Adult Patients with Narcolepsy
Dosage for Pediatric Patients with Narcolepsy (7 Years of Age and Older)
* The recommended starting dosage, titration regimen, and maximum total nightly dosage are based on body weight (2.2).
Dosage for Adult Patients with Idiopathic Hypersomnia
* XYWAV can be administered as a twice or once nightly regimen in adults .* Twice nightly: Initiate dosage at 4.5 g or less per night orally, divided into two doses. Titrate to effect in increments of up to 1.5 g per night per week, up to 9 g total nightly dose .* Once nightly: Initiate dosage at 3 g or less per night orally, as one dose. Titrate to effect in increments of up to 1.5 g per night per week, up to 6 g total nightly dose .
Important Administration Information
* Administer XYWAV at least 2 hours after eating .* Prepare XYWAV prior to bedtime; dilute with approximately ¼ cup of water in pharmacy-provided containers .* Take XYWAV while in bed and lie down after dosing .
For Patients Transitioning from Xyrem to XYWAV: Initiate at the same dose and regimen as Xyrem (gram for gram). Titrate as needed based on efficacy and tolerability .
Patients with Hepatic Impairment
Recommended starting dosage is one-half of the original dosage per night administered orally, divided into two doses .
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drug label
Xywav prescribing information
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You can report a Xywav adverse event on MedWatch, the FDA's medical product safety reporting program for health professionals, patients and consumers.
samples
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NOT PROVIDED BY BRANDView Online Sample Form
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Your rep will communicate with you how to receive samples, when you can receive samples, the amount and more.
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Not sure who your local Xywav pharma rep is? Reach out to Jazz Pharmaceuticals, Inc. and they can help you identify your rep.
prior authorization
Xywav Prior authorization resources
NOT PROVIDED BY BRANDComplete Letter of Medical Necessity
NOT PROVIDED BY BRANDCoverage Authorization Request
NOT PROVIDED BY BRANDComplete Coverage Authorization appeals
Guide to Completing Prior Authorization - Narcolepsy
Letter of Medical Necessity - Narcolepsy
Letter of Medical Necessity - Idiopathic Hypersomnia
Formulary Exception Process Guide
Guide to Completing Prior Authorization - Idiopathic Hypersomnia
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If available, these templates are provided by the brand to help you navigate insurance, especially with newer drugs.
Benefits investigation
NOT PROVIDED BY BRANDBenefits investigation resources
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Benefits investigations are conducted to determine whether a therapy is covered under a patient's insurance, if a prior authorization is required, and which specialty pharmacies are preferred.
Reimbursement help (FRM)
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Some brands offer a field reimbursement manager who will work with your clinical staff and preferred pharmacy to help make sure patients don't fall through the cracks.
financial assistance
Xywav Financial assistance options
Co-pay savings program
commercial only
Enroll in Patient Savings Program
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Overview
Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)
Patient benefit
A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max
Patient eligibility
Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance
How to sign up
Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form
Bridge program
commercial only
Enroll in Bridge Program
Quick Start Voucher Program
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Overview
Provide patient immediate access to therapy during an insurance delay (typically new starts; some may cover change in insurance)
Limited time/ fill (typically 7-30 days; some may offer additional fill for continued delay up to certain limit)
Patient benefit
100% free (outside of insurance)
Patient eligibility
HCP must enroll patient
May be limited to commercially insured patients (i.e., no government beneficiaries); some programs may allow government beneficiaries
How to sign up
Typically HCP assisted enrollment (via form)
Foundation programs
under insured
no insurance
goverment insurance
65+
JazzCares Patient Assistance Program Application - Online
JazzCares Patient Assistance Program Application - Print Form
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Overview
Charitable 501(c)(3) organizations provide direct cost-sharing and other support (e.g., travel, counseling) through disease-state funds to indigent patients on first-come first-served basis
These organizations may receive financial contributions from drug manaufacturers for particular disease-state funds that cannot provide funds directly to patients - the foundation must be independent/unaligned
Patient benefit
Patients apply for grants that cover a portion (or all) of their out-of-pocket costs (deductibles and co-pays) until the grant is exhausted
Patient eligibility
Patients must apply and meet eligibility criteria including income level (typically a multiple of federal poverty line), specific diagnosis, insurance status, etc.
How to sign up
Patients submit proof of out-of-pocket drug costs to charities for reimbursement
patient education
Xywav Patient education
Getting started on Xywav
NOT PROVIDED BY BRANDInstructions For Use - Narcolepsy
NOT PROVIDED BY BRANDInstructions For Use - Idiopathic Hypersomnia (IH)
Patient toolkit
About Xywav - Narcolepsy
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
About Xywav - Idiopathic Hypersomnia (IH)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Resources - Narcolepsy
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
Patient Resources - Idiopathic Hypersomnia (IH)
ASK PATIENT TO: Open Camera on Phone Scan QR Code & Tap Link
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Other resources brands publish to help support patients and caregivers.
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Access to a Field Reimbursement Manager (FRM) or Medical Science Liaison (MSL) varies by brand and may require talking with your rep first.
Samples are provided at the discretion of the brand.
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