Serotonin 1b Receptor Agonists

Serotonin 1d Receptor Agonists

Serotonin-1b and Serotonin-1d Receptor Agonist

Cluster Headache

Migraine Disorders

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">ZEMBRACE SymTouch injection contains sumatriptan succinate, a selective 5-HT<span class="Sub">1B/1D</span> receptor agonist. Sumatriptan succinate is chemically designated as 3-[2-(dimethylamino) ethyl]-N-methyl-indole-5-methanesulfonamide succinate (1:1), and it has the following structure:</p><div class="Figure"><img alt="Chemical Structure" src="zembrace-01.jpg"/></div><p>The empirical formula is C<span class="Sub">14</span>H<span class="Sub">21</span>N<span class="Sub">3</span>O<span class="Sub">2</span>S∙C<span class="Sub">4</span>H<span class="Sub">6</span>O<span class="Sub">4</span>, representing a molecular weight of 413.5. Sumatriptan succinate is a white to off-white powder that is readily soluble in water and in saline.</p><p>ZEMBRACE SymTouch is a clear, colorless to pale yellow, sterile, nonpyrogenic solution for subcutaneous injection. Each 0.5 mL of ZEMBRACE SymTouch contains 4.2 mg of sumatriptan succinate equivalent to 3 mg of sumatriptan (base) and 4.15 mg of sodium chloride, USP in Water for Injection, USP.</p><p>The pH range of solution is approximately 4.2 to 5.3 and the osmolality of injection is approximately 291 mOsmol (275 to 315 mOsmol).</p></section>

ZEMBRACE SYMTOUCH

0.5 ML sumatriptan 6 MG/ML Auto-Injector

Zembrace

0.5 ML sumatriptan 6 MG/ML Auto-Injector [Zembrace]

sumatriptan

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information 

Medication Guide 

Pharmacy List 

Prior Authorization Guide 

Coverage Authorization Request 

Coverage Authorization Appeals

Letter of Medical Necessity 

Enroll in Patient Savings Program 

About Zembrace SymTouch 

Instructions For Use: Migraine 

Zembrace SymTouch Start Guide 

Patient Brochure 

Migraine Tracker 

Doctor Discussion Guide 