| Acne Vulgaris
Absorica vs Tazorac
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Absorica Ld vs Tazorac with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsTazorac has a higher rate of injection site reactions vs Absorica Ld based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Tazorac but not Absorica Ld, including UnitedHealthcare
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Category
Absorica Ld
Tazorac
At A Glance
Oral
Twice daily
Retinoid
Topical
Daily
Retinoid
Indications
- Acne Vulgaris
- Psoriasis vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris ABSORICA: 0.5 to 1 mg/kg/day in two divided doses for 15 to 20 weeks (up to 2 mg/kg/day for severe disease with scarring or trunk involvement); ABSORICA LD: 0.4 to 0.8 mg/kg/day in two divided doses for 15 to 20 weeks (up to 1.6 mg/kg/day for severe disease).
Psoriasis vulgaris Apply a thin film (2 mg/cm2) of 0.05% cream once daily in the evening to psoriatic lesions only; increase to 0.1% if tolerated and medically indicated.
Acne Vulgaris Apply a thin layer (2 mg/cm2) of 0.1% cream once daily in the evening to affected facial skin areas after gentle cleansing and drying.
Contraindications
- Pregnancy
- Hypersensitivity to isotretinoin, Vitamin A (given chemical similarity), or any component of the product
- Pregnancy (retinoids may cause fetal harm)
- Known hypersensitivity to any component of TAZORAC Cream
Adverse Reactions
Most common Cheilitis, hypertriglyceridemia, dry skin, dry lips, fatigue, headache, epistaxis, arthralgia, back pain, musculoskeletal pain
Serious Embryo-fetal toxicity, psychiatric disorders (including suicidal ideation, depression, psychosis), intracranial hypertension, serious skin reactions, pancreatitis, hepatotoxicity, inflammatory bowel disease, musculoskeletal abnormalities, hearing impairment, hypersensitivity reactions
Most common (>=10%) Psoriasis: pruritus, erythema, burning; Acne: desquamation, dry skin, erythema, burning sensation
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Postmarketing Blister, dermatitis, urticaria, skin exfoliation, skin discoloration (hyperpigmentation or hypopigmentation), swelling at or near application sites, pain
Pharmacology
Isotretinoin is a retinoid that inhibits sebaceous gland function and keratinization; clinical improvement in nodular acne is associated with a reduction in sebum secretion, reflecting reduced sebaceous gland size and inhibition of sebaceous gland differentiation.
Tazarotene is a retinoid prodrug converted by esterase hydrolysis to tazarotenic acid, which binds retinoic acid receptors RAR-beta and RAR-gamma with relative selectivity and may modify gene expression in psoriatic and acne-affected skin.
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Most Common Insurance
Anthem BCBS
Absorica Ld
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (0/12) · Qty limit (0/12)
No coverage data available for Tazorac.
UnitedHealthcare
Absorica Ld
- Covered on 4 commercial plans
- PA (2/8) · Step Therapy (0/8) · Qty limit (0/8)
No coverage data available for Tazorac.
Humana
Absorica Ld
- Covered on 0 commercial plans
- PA (0/3) · Step Therapy (0/3) · Qty limit (0/3)
No coverage data available for Tazorac.
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Absorica Ld.
No savings programs available for Tazorac.
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Absorica LdView full Absorica Ld profile
TazoracView full Tazorac profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.