| Acne Vulgaris
Aczone vs Amzeeq
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Aczone vs Amzeeq with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsAmzeeq has a higher rate of injection site reactions vs Aczone based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Amzeeq but not Aczone, including UnitedHealthcare
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Category
Aczone
Amzeeq
At A Glance
Topical
Daily
Sulfone
Topical
Daily
Tetracycline antibiotic
Indications
- Acne Vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris Apply approximately a pea-sized amount of ACZONE Gel, 7.5% in a thin layer to the entire face once daily; a thin layer may also be applied to other affected areas once daily.
Acne Vulgaris Apply a small (cherry-sized) amount of foam to acne-affected areas of the face and body once daily, at least 1 hour before bedtime; do not bathe, shower, or swim for at least 1 hour after application.
Contraindications
—
- Hypersensitivity to any tetracycline or any other ingredient in AMZEEQ
Adverse Reactions
Most common (>=0.9%) Application site dryness, application site pruritus
Serious Agranulocytosis, hemolytic anemia, peripheral neuropathy, toxic epidermal necrolysis, erythema multiforme, bullous and exfoliative dermatitis, erythema nodosum, urticaria (reported with oral use of dapsone)
Postmarketing Methemoglobinemia, rash (including erythematous rash, application site rash), swelling of face (including lip swelling, eye swelling)
Most common (>=1%) Headache
Pharmacology
Dapsone is a sulfone whose mechanism of action in treating acne vulgaris is not known; topical application results in minimal systemic absorption.
Tetracycline-class antibiotic; the mechanism of action of AMZEEQ for treatment of acne is unknown, though minocycline is active in vitro against most isolates of Propionibacterium acnes.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Aczone
- Covered on 5 commercial plans
- PA (5/12) · Step Therapy (5/12) · Qty limit (9/12)
Amzeeq
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
UnitedHealthcare
Aczone
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
Amzeeq
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
Humana
Aczone
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (2/3)
Amzeeq
- Covered on 0 commercial plans
- PA (2/3) · Step Therapy (2/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Aczone.
No savings programs available for Amzeeq.
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AczoneView full Aczone profile
AmzeeqView full Amzeeq profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.