| Acne Vulgaris
Aczone vs Arazlo
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Aczone vs Arazlo with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsArazlo has a higher rate of injection site reactions vs Aczone based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Arazlo but not Aczone, including UnitedHealthcare
Sign up to reveal the full AI analysis
Category
Aczone
Arazlo
At A Glance
Topical
Daily
Sulfone
Topical
Daily
Retinoid
Indications
- Acne Vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris Apply approximately a pea-sized amount of ACZONE Gel, 7.5% in a thin layer to the entire face once daily; a thin layer may also be applied to other affected areas once daily.
Acne Vulgaris Apply a thin layer to affected areas once daily; avoid eyes, mouth, paranasal creases, and mucous membranes; not for oral, ophthalmic, or intravaginal use.
Contraindications
—
- Pregnancy (may cause fetal harm)
Adverse Reactions
Most common (>=0.9%) Application site dryness, application site pruritus
Serious Agranulocytosis, hemolytic anemia, peripheral neuropathy, toxic epidermal necrolysis, erythema multiforme, bullous and exfoliative dermatitis, erythema nodosum, urticaria (reported with oral use of dapsone)
Postmarketing Methemoglobinemia, rash (including erythematous rash, application site rash), swelling of face (including lip swelling, eye swelling)
Most common (>=1%) Application site pain, application site dryness, application site exfoliation, application site erythema, application site pruritus
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Pharmacology
Dapsone is a sulfone whose mechanism of action in treating acne vulgaris is not known; topical application results in minimal systemic absorption.
Tazarotene is a retinoid prodrug converted by deesterification to tazarotenic acid, which binds to retinoic acid receptors RARalpha, RARbeta, and RARgamma with relative selectivity for RARbeta and RARgamma, potentially modifying gene expression.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Aczone
- Covered on 5 commercial plans
- PA (5/12) · Step Therapy (5/12) · Qty limit (9/12)
Arazlo
- Covered on 5 commercial plans
- PA (6/12) · Step Therapy (10/12) · Qty limit (9/12)
UnitedHealthcare
Aczone
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
Arazlo
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Aczone
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (2/3)
Arazlo
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Aczone.
No savings programs available for Arazlo.
Compare Other Drugs
Let us handle your prior authsJust enter your patient's info and we'll:
- Verify eligibility with the payer.
- Pull the right PA forms directly from the payer.
- Submit, track & send live updates to your dashboard.
Free to start · HIPAA compliant
Next Steps for Your Patient
AczoneView full Aczone profile
ArazloView full Arazlo profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.