| Acne Vulgaris
Aczone vs Fabior
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Aczone vs Fabior with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsFabior has a higher rate of injection site reactions vs Aczone based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Fabior but not Aczone, including UnitedHealthcare
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Category
Aczone
Fabior
At A Glance
Topical
Daily
Sulfone
Topical
Daily
Retinoid
Indications
- Acne Vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris Apply approximately a pea-sized amount of ACZONE Gel, 7.5% in a thin layer to the entire face once daily; a thin layer may also be applied to other affected areas once daily.
Acne Vulgaris Apply once daily in the evening to affected areas of face and/or upper trunk after washing with a mild cleanser and fully drying; use a thin layer and massage until foam disappears.
Contraindications
—
- Pregnancy (tazarotene is teratogenic and may cause fetal harm)
Adverse Reactions
Most common (>=0.9%) Application site dryness, application site pruritus
Serious Agranulocytosis, hemolytic anemia, peripheral neuropathy, toxic epidermal necrolysis, erythema multiforme, bullous and exfoliative dermatitis, erythema nodosum, urticaria (reported with oral use of dapsone)
Postmarketing Methemoglobinemia, rash (including erythematous rash, application site rash), swelling of face (including lip swelling, eye swelling)
Most common (>=6%) Application site irritation, application site dryness, application site erythema, application site exfoliation
Pharmacology
Dapsone is a sulfone whose mechanism of action in treating acne vulgaris is not known; topical application results in minimal systemic absorption.
Tazarotene is a retinoid prodrug converted by rapid deesterification to tazarotenic acid, which binds retinoic acid receptors (RARalpha, RARbeta, RARgamma) with relative selectivity for RARbeta and RARgamma; its therapeutic effect in acne vulgaris may be due to anti-hyperproliferative, normalizing-of-differentiation, and anti-inflammatory effects.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Aczone
- Covered on 5 commercial plans
- PA (5/12) · Step Therapy (5/12) · Qty limit (9/12)
Fabior
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (9/12) · Qty limit (0/12)
UnitedHealthcare
Aczone
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
Fabior
- Covered on 4 commercial plans
- PA (1/8) · Step Therapy (0/8) · Qty limit (1/8)
Humana
Aczone
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (2/3)
Fabior
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Aczone.
No savings programs available for Fabior.
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AczoneView full Aczone profile
FabiorView full Fabior profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.