| Acne Vulgaris

Altreno vs Winlevi

Side-by-side clinical, coverage, and cost comparison for acne vulgaris.
Deep comparison between: Altreno vs Winlevi with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.
Safety signalsWinlevi has a higher rate of injection site reactions vs Altreno based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Winlevi but not Altreno, including UnitedHealthcare
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Altreno
Winlevi
At A Glance
Topical
Daily
Retinoid
Topical
Twice daily
Androgen receptor inhibitor
Indications
  • Acne Vulgaris
  • Acne Vulgaris
Dosing
Acne Vulgaris Apply a thin layer to the affected areas once daily; avoid the eyes, mouth, paranasal creases, and mucous membranes.
Acne Vulgaris Apply a thin uniform layer twice daily (morning and evening) to the affected area after gently cleansing and drying the skin; for topical use only.
Contraindications
—
—
Adverse Reactions
Most common (>=1%) Application site dryness, pain, erythema, irritation, exfoliation
Most common (>=7%) erythema/redness, pruritus, scaling/dryness
Other edema, stinging/burning, skin atrophy, striae rubrae, telangiectasia, hyperkalemia, polycystic ovaries, amenorrhea
Pharmacology
Retinoid; topical tretinoin binds retinoic acid nuclear receptors (RARalpha, RARbeta, RARgamma) to modify gene expression and epithelial cell differentiation, reducing microcomedo formation and promoting comedone extrusion.
Clascoterone is an androgen receptor inhibitor; the exact mechanism of action of WINLEVI cream for the topical treatment of acne vulgaris is unknown.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Altreno
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (9/12) · Qty limit (9/12)
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Winlevi
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
View full coverage details ›
UnitedHealthcare
Altreno
  • Covered on 4 commercial plans
  • PA (1/8) · Step Therapy (0/8) · Qty limit (0/8)
View full coverage details ›
Winlevi
  • Covered on 4 commercial plans
  • PA (1/8) · Step Therapy (0/8) · Qty limit (0/8)
View full coverage details ›
Humana
Altreno
  • Covered on 0 commercial plans
  • PA (3/3) · Step Therapy (0/3) · Qty limit (2/3)
View full coverage details ›
Winlevi
  • Covered on 0 commercial plans
  • PA (3/3) · Step Therapy (2/3) · Qty limit (0/3)
View full coverage details ›
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Altreno.
No savings programs available for Winlevi.
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AltrenoView full Altreno profile
WinleviView full Winlevi profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.