| Acne Vulgaris

Amzeeq vs Arazlo

Side-by-side clinical, coverage, and cost comparison for acne vulgaris.
Deep comparison between: Amzeeq vs Arazlo with Prescriber.AI
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Safety signalsArazlo has a higher rate of injection site reactions vs Amzeeq based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Arazlo but not Amzeeq, including UnitedHealthcare
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Amzeeq
Arazlo
At A Glance
Topical
Daily
Tetracycline antibiotic
Topical
Daily
Retinoid
Indications
  • Acne Vulgaris
  • Acne Vulgaris
Dosing
Acne Vulgaris Apply a small (cherry-sized) amount of foam to acne-affected areas of the face and body once daily, at least 1 hour before bedtime; do not bathe, shower, or swim for at least 1 hour after application.
Acne Vulgaris Apply a thin layer to affected areas once daily; avoid eyes, mouth, paranasal creases, and mucous membranes; not for oral, ophthalmic, or intravaginal use.
Contraindications
  • Hypersensitivity to any tetracycline or any other ingredient in AMZEEQ
  • Pregnancy (may cause fetal harm)
Adverse Reactions
Most common (>=1%) Headache
Most common (>=1%) Application site pain, application site dryness, application site exfoliation, application site erythema, application site pruritus
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Pharmacology
Tetracycline-class antibiotic; the mechanism of action of AMZEEQ for treatment of acne is unknown, though minocycline is active in vitro against most isolates of Propionibacterium acnes.
Tazarotene is a retinoid prodrug converted by deesterification to tazarotenic acid, which binds to retinoic acid receptors RARalpha, RARbeta, and RARgamma with relative selectivity for RARbeta and RARgamma, potentially modifying gene expression.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Amzeeq
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
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Arazlo
  • Covered on 5 commercial plans
  • PA (6/12) · Step Therapy (10/12) · Qty limit (9/12)
View full coverage details ›
UnitedHealthcare
Amzeeq
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
View full coverage details ›
Arazlo
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
View full coverage details ›
Humana
Amzeeq
  • Covered on 0 commercial plans
  • PA (2/3) · Step Therapy (2/3) · Qty limit (2/3)
View full coverage details ›
Arazlo
  • Covered on 0 commercial plans
  • PA (3/3) · Step Therapy (3/3) · Qty limit (0/3)
View full coverage details ›
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Amzeeq.
No savings programs available for Arazlo.
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AmzeeqView full Amzeeq profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.