| Acne Vulgaris

Amzeeq vs Fabior

Side-by-side clinical, coverage, and cost comparison for acne vulgaris.
Deep comparison between: Amzeeq vs Fabior with Prescriber.AI
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Safety signalsFabior has a higher rate of injection site reactions vs Amzeeq based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Fabior but not Amzeeq, including UnitedHealthcare
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Amzeeq
Fabior
At A Glance
Topical
Daily
Tetracycline antibiotic
Topical
Daily
Retinoid
Indications
  • Acne Vulgaris
  • Acne Vulgaris
Dosing
Acne Vulgaris Apply a small (cherry-sized) amount of foam to acne-affected areas of the face and body once daily, at least 1 hour before bedtime; do not bathe, shower, or swim for at least 1 hour after application.
Acne Vulgaris Apply once daily in the evening to affected areas of face and/or upper trunk after washing with a mild cleanser and fully drying; use a thin layer and massage until foam disappears.
Contraindications
  • Hypersensitivity to any tetracycline or any other ingredient in AMZEEQ
  • Pregnancy (tazarotene is teratogenic and may cause fetal harm)
Adverse Reactions
Most common (>=1%) Headache
Most common (>=6%) Application site irritation, application site dryness, application site erythema, application site exfoliation
Pharmacology
Tetracycline-class antibiotic; the mechanism of action of AMZEEQ for treatment of acne is unknown, though minocycline is active in vitro against most isolates of Propionibacterium acnes.
Tazarotene is a retinoid prodrug converted by rapid deesterification to tazarotenic acid, which binds retinoic acid receptors (RARalpha, RARbeta, RARgamma) with relative selectivity for RARbeta and RARgamma; its therapeutic effect in acne vulgaris may be due to anti-hyperproliferative, normalizing-of-differentiation, and anti-inflammatory effects.
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Most Common Insurance
Anthem BCBS
Amzeeq
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
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Fabior
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (9/12) · Qty limit (0/12)
View full coverage details ›
UnitedHealthcare
Amzeeq
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
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Fabior
  • Covered on 4 commercial plans
  • PA (1/8) · Step Therapy (0/8) · Qty limit (1/8)
View full coverage details ›
Humana
Amzeeq
  • Covered on 0 commercial plans
  • PA (2/3) · Step Therapy (2/3) · Qty limit (2/3)
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Fabior
  • Covered on 0 commercial plans
  • PA (3/3) · Step Therapy (3/3) · Qty limit (2/3)
View full coverage details ›
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Amzeeq.
No savings programs available for Fabior.
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AmzeeqView full Amzeeq profile
FabiorView full Fabior profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.