| Acne Vulgaris
Arazlo vs Epiduo Forte
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Arazlo vs Epiduo with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsEpiduo has a higher rate of injection site reactions vs Arazlo based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Epiduo but not Arazlo, including UnitedHealthcare
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Category
Arazlo
Epiduo
At A Glance
Topical
Daily
Retinoid
Topical
Daily
Retinoid + benzoyl peroxide combination
Indications
- Acne Vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris Apply a thin layer to affected areas once daily; avoid eyes, mouth, paranasal creases, and mucous membranes; not for oral, ophthalmic, or intravaginal use.
Acne Vulgaris Apply a thin film once daily after washing to affected areas of the face and/or trunk; use a pea-sized amount for each area of the face.
Contraindications
- Pregnancy (may cause fetal harm)
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Adverse Reactions
Most common (>=1%) Application site pain, application site dryness, application site exfoliation, application site erythema, application site pruritus
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Most common (>=1%) Dry skin, contact dermatitis, application site burning, application site irritation, skin irritation
Postmarketing Eyelid edema, sunburn, blister, pain of skin, pruritus, swelling face, conjunctivitis, skin discoloration, rash, eczema, throat tightness, allergic contact dermatitis
Pharmacology
Tazarotene is a retinoid prodrug converted by deesterification to tazarotenic acid, which binds to retinoic acid receptors RARalpha, RARbeta, and RARgamma with relative selectivity for RARbeta and RARgamma, potentially modifying gene expression.
Adapalene is a retinoid that modulates cellular differentiation, keratinization, and inflammatory processes; benzoyl peroxide is an oxidizing agent with bactericidal and keratolytic effects.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Arazlo
- Covered on 5 commercial plans
- PA (6/12) · Step Therapy (10/12) · Qty limit (9/12)
Epiduo
- Covered on 5 commercial plans
- PA (9/12) · Step Therapy (0/12) · Qty limit (9/12)
UnitedHealthcare
Arazlo
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Epiduo
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (5/8)
Humana
Arazlo
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (0/3)
Epiduo
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Arazlo.
No savings programs available for Epiduo.
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ArazloView full Arazlo profile
EpiduoView full Epiduo profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.