| Acne Vulgaris
Arazlo vs Fabior
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Arazlo vs Fabior with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsFabior has a higher rate of injection site reactions vs Arazlo based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Fabior but not Arazlo, including UnitedHealthcare
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Category
Arazlo
Fabior
At A Glance
Topical
Daily
Retinoid
Topical
Daily
Retinoid
Indications
- Acne Vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris Apply a thin layer to affected areas once daily; avoid eyes, mouth, paranasal creases, and mucous membranes; not for oral, ophthalmic, or intravaginal use.
Acne Vulgaris Apply once daily in the evening to affected areas of face and/or upper trunk after washing with a mild cleanser and fully drying; use a thin layer and massage until foam disappears.
Contraindications
- Pregnancy (may cause fetal harm)
- Pregnancy (tazarotene is teratogenic and may cause fetal harm)
Adverse Reactions
Most common (>=1%) Application site pain, application site dryness, application site exfoliation, application site erythema, application site pruritus
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Most common (>=6%) Application site irritation, application site dryness, application site erythema, application site exfoliation
Pharmacology
Tazarotene is a retinoid prodrug converted by deesterification to tazarotenic acid, which binds to retinoic acid receptors RARalpha, RARbeta, and RARgamma with relative selectivity for RARbeta and RARgamma, potentially modifying gene expression.
Tazarotene is a retinoid prodrug converted by rapid deesterification to tazarotenic acid, which binds retinoic acid receptors (RARalpha, RARbeta, RARgamma) with relative selectivity for RARbeta and RARgamma; its therapeutic effect in acne vulgaris may be due to anti-hyperproliferative, normalizing-of-differentiation, and anti-inflammatory effects.
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Most Common Insurance
Anthem BCBS
Arazlo
- Covered on 5 commercial plans
- PA (6/12) · Step Therapy (10/12) · Qty limit (9/12)
Fabior
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (9/12) · Qty limit (0/12)
UnitedHealthcare
Arazlo
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Fabior
- Covered on 4 commercial plans
- PA (1/8) · Step Therapy (0/8) · Qty limit (1/8)
Humana
Arazlo
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (0/3)
Fabior
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Arazlo.
No savings programs available for Fabior.
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ArazloView full Arazlo profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.