| Acne Vulgaris

Arazlo vs Tazorac

Side-by-side clinical, coverage, and cost comparison for acne vulgaris.
Deep comparison between: Arazlo vs Tazorac with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.
Safety signalsTazorac has a higher rate of injection site reactions vs Arazlo based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Tazorac but not Arazlo, including UnitedHealthcare
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Arazlo
Tazorac
At A Glance
Topical
Daily
Retinoid
Topical
Daily
Retinoid
Indications
  • Acne Vulgaris
  • Psoriasis vulgaris
  • Acne Vulgaris
Dosing
Acne Vulgaris Apply a thin layer to affected areas once daily; avoid eyes, mouth, paranasal creases, and mucous membranes; not for oral, ophthalmic, or intravaginal use.
Psoriasis vulgaris Apply a thin film (2 mg/cm2) of 0.05% cream once daily in the evening to psoriatic lesions only; increase to 0.1% if tolerated and medically indicated.
Acne Vulgaris Apply a thin layer (2 mg/cm2) of 0.1% cream once daily in the evening to affected facial skin areas after gentle cleansing and drying.
Contraindications
  • Pregnancy (may cause fetal harm)
  • Pregnancy (retinoids may cause fetal harm)
  • Known hypersensitivity to any component of TAZORAC Cream
Adverse Reactions
Most common (>=1%) Application site pain, application site dryness, application site exfoliation, application site erythema, application site pruritus
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Most common (>=10%) Psoriasis: pruritus, erythema, burning; Acne: desquamation, dry skin, erythema, burning sensation
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Postmarketing Blister, dermatitis, urticaria, skin exfoliation, skin discoloration (hyperpigmentation or hypopigmentation), swelling at or near application sites, pain
Pharmacology
Tazarotene is a retinoid prodrug converted by deesterification to tazarotenic acid, which binds to retinoic acid receptors RARalpha, RARbeta, and RARgamma with relative selectivity for RARbeta and RARgamma, potentially modifying gene expression.
Tazarotene is a retinoid prodrug converted by esterase hydrolysis to tazarotenic acid, which binds retinoic acid receptors RAR-beta and RAR-gamma with relative selectivity and may modify gene expression in psoriatic and acne-affected skin.
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Most Common Insurance
Anthem BCBS
Arazlo
  • Covered on 5 commercial plans
  • PA (6/12) · Step Therapy (10/12) · Qty limit (9/12)
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No coverage data available for Tazorac.
UnitedHealthcare
Arazlo
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
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No coverage data available for Tazorac.
Humana
Arazlo
  • Covered on 0 commercial plans
  • PA (3/3) · Step Therapy (3/3) · Qty limit (0/3)
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No coverage data available for Tazorac.
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Arazlo.
No savings programs available for Tazorac.
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ArazloView full Arazlo profile
TazoracView full Tazorac profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.