| Acne Vulgaris
Epiduo Forte vs Winlevi
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Epiduo vs Winlevi with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsWinlevi has a higher rate of injection site reactions vs Epiduo based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Winlevi but not Epiduo, including UnitedHealthcare
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Category
Epiduo
Winlevi
At A Glance
Topical
Daily
Retinoid + benzoyl peroxide combination
Topical
Twice daily
Androgen receptor inhibitor
Indications
- Acne Vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris Apply a thin film once daily after washing to affected areas of the face and/or trunk; use a pea-sized amount for each area of the face.
Acne Vulgaris Apply a thin uniform layer twice daily (morning and evening) to the affected area after gently cleansing and drying the skin; for topical use only.
Contraindications
—
—
Adverse Reactions
Most common (>=1%) Dry skin, contact dermatitis, application site burning, application site irritation, skin irritation
Postmarketing Eyelid edema, sunburn, blister, pain of skin, pruritus, swelling face, conjunctivitis, skin discoloration, rash, eczema, throat tightness, allergic contact dermatitis
Most common (>=7%) erythema/redness, pruritus, scaling/dryness
Other edema, stinging/burning, skin atrophy, striae rubrae, telangiectasia, hyperkalemia, polycystic ovaries, amenorrhea
Pharmacology
Adapalene is a retinoid that modulates cellular differentiation, keratinization, and inflammatory processes; benzoyl peroxide is an oxidizing agent with bactericidal and keratolytic effects.
Clascoterone is an androgen receptor inhibitor; the exact mechanism of action of WINLEVI cream for the topical treatment of acne vulgaris is unknown.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Epiduo
- Covered on 5 commercial plans
- PA (9/12) · Step Therapy (0/12) · Qty limit (9/12)
Winlevi
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
UnitedHealthcare
Epiduo
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (5/8)
Winlevi
- Covered on 4 commercial plans
- PA (1/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Epiduo
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (2/3)
Winlevi
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (2/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Epiduo.
No savings programs available for Winlevi.
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EpiduoView full Epiduo profile
WinleviView full Winlevi profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.