| Acne Vulgaris
Fabior vs Onexton
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Fabior vs Onexton with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsOnexton has a higher rate of injection site reactions vs Fabior based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Onexton but not Fabior, including UnitedHealthcare
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Category
Fabior
Onexton
At A Glance
Topical
Daily
Retinoid
Topical
Once daily
Antibiotic/keratolytic combination
Indications
- Acne Vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris Apply once daily in the evening to affected areas of face and/or upper trunk after washing with a mild cleanser and fully drying; use a thin layer and massage until foam disappears.
Acne Vulgaris Apply a pea-sized amount to the face once daily; wash face gently with mild soap, rinse with warm water, and pat dry before applying. Avoid eyes, mouth, mucous membranes, and areas of broken skin.
Contraindications
- Pregnancy (tazarotene is teratogenic and may cause fetal harm)
- Hypersensitivity (e.g., anaphylaxis) to clindamycin, benzoyl peroxide, any components of the formulation, or lincomycin
- History of regional enteritis, ulcerative colitis, or antibiotic-associated colitis
Adverse Reactions
Most common (>=6%) Application site irritation, application site dryness, application site erythema, application site exfoliation
Most common (<0.5%) Burning sensation, contact dermatitis, pruritus, rash
Postmarketing Anaphylaxis, allergic reactions leading to hospitalization
Pharmacology
Tazarotene is a retinoid prodrug converted by rapid deesterification to tazarotenic acid, which binds retinoic acid receptors (RARalpha, RARbeta, RARgamma) with relative selectivity for RARbeta and RARgamma; its therapeutic effect in acne vulgaris may be due to anti-hyperproliferative, normalizing-of-differentiation, and anti-inflammatory effects.
Clindamycin is a lincosamide antibacterial that binds to the 50S ribosomal subunit of susceptible bacteria and suppresses protein synthesis by interfering with peptidyl transfer; benzoyl peroxide is an oxidizing agent with bactericidal and keratolytic effects, though its precise mechanism is unknown.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Fabior
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (9/12) · Qty limit (0/12)
Onexton
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
UnitedHealthcare
Fabior
- Covered on 4 commercial plans
- PA (1/8) · Step Therapy (0/8) · Qty limit (1/8)
Onexton
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (1/8) · Qty limit (0/8)
Humana
Fabior
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (2/3)
Onexton
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Fabior.
No savings programs available for Onexton.
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FabiorView full Fabior profile
OnextonView full Onexton profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.