| Acne Vulgaris
Fabior vs Seysara
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Fabior vs Seysara with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsSeysara has a higher rate of injection site reactions vs Fabior based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Seysara but not Fabior, including UnitedHealthcare
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Category
Fabior
Seysara
At A Glance
Topical
Daily
Retinoid
Oral
Daily
Tetracycline-class antibiotic
Indications
- Acne Vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris Apply once daily in the evening to affected areas of face and/or upper trunk after washing with a mild cleanser and fully drying; use a thin layer and massage until foam disappears.
Acne Vulgaris Weight-based once-daily oral dosing: 60 mg (33-54 kg), 100 mg (55-84 kg), or 150 mg (85-136 kg); take with or without food and adequate fluid; reassess if no improvement after 12 weeks.
Contraindications
- Pregnancy (tazarotene is teratogenic and may cause fetal harm)
- Hypersensitivity to any tetracycline
Adverse Reactions
Most common (>=6%) Application site irritation, application site dryness, application site erythema, application site exfoliation
Most common (>=1%) Nausea
Less common (<1%, female subjects) Vulvovaginal mycotic infection, vulvovaginal candidiasis
Pharmacology
Tazarotene is a retinoid prodrug converted by rapid deesterification to tazarotenic acid, which binds retinoic acid receptors (RARalpha, RARbeta, RARgamma) with relative selectivity for RARbeta and RARgamma; its therapeutic effect in acne vulgaris may be due to anti-hyperproliferative, normalizing-of-differentiation, and anti-inflammatory effects.
Sarecycline is an aminomethylcycline within the tetracycline class that binds to the 30S ribosomal subunit and blocks protein synthesis in Propionibacterium acnes; its precise mechanism for treating the inflammatory lesions of non-nodular acne vulgaris is not known.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Fabior
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (9/12) · Qty limit (0/12)
Seysara
- Covered on 5 commercial plans
- PA (9/12) · Step Therapy (9/12) · Qty limit (9/12)
UnitedHealthcare
Fabior
- Covered on 4 commercial plans
- PA (1/8) · Step Therapy (0/8) · Qty limit (1/8)
Seysara
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Fabior
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (2/3)
Seysara
- Covered on 0 commercial plans
- PA (0/3) · Step Therapy (2/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Fabior.
No savings programs available for Seysara.
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FabiorView full Fabior profile
SeysaraView full Seysara profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.