| Acne Vulgaris
Seysara vs Tazorac
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Seysara vs Tazorac with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsTazorac has a higher rate of injection site reactions vs Seysara based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Tazorac but not Seysara, including UnitedHealthcare
Sign up to reveal the full AI analysis
Category
Seysara
Tazorac
At A Glance
Oral
Daily
Tetracycline-class antibiotic
Topical
Daily
Retinoid
Indications
- Acne Vulgaris
- Psoriasis vulgaris
- Acne Vulgaris
Dosing
Acne Vulgaris Weight-based once-daily oral dosing: 60 mg (33-54 kg), 100 mg (55-84 kg), or 150 mg (85-136 kg); take with or without food and adequate fluid; reassess if no improvement after 12 weeks.
Psoriasis vulgaris Apply a thin film (2 mg/cm2) of 0.05% cream once daily in the evening to psoriatic lesions only; increase to 0.1% if tolerated and medically indicated.
Acne Vulgaris Apply a thin layer (2 mg/cm2) of 0.1% cream once daily in the evening to affected facial skin areas after gentle cleansing and drying.
Contraindications
- Hypersensitivity to any tetracycline
- Pregnancy (retinoids may cause fetal harm)
- Known hypersensitivity to any component of TAZORAC Cream
Adverse Reactions
Most common (>=1%) Nausea
Less common (<1%, female subjects) Vulvovaginal mycotic infection, vulvovaginal candidiasis
Most common (>=10%) Psoriasis: pruritus, erythema, burning; Acne: desquamation, dry skin, erythema, burning sensation
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Postmarketing Blister, dermatitis, urticaria, skin exfoliation, skin discoloration (hyperpigmentation or hypopigmentation), swelling at or near application sites, pain
Pharmacology
Sarecycline is an aminomethylcycline within the tetracycline class that binds to the 30S ribosomal subunit and blocks protein synthesis in Propionibacterium acnes; its precise mechanism for treating the inflammatory lesions of non-nodular acne vulgaris is not known.
Tazarotene is a retinoid prodrug converted by esterase hydrolysis to tazarotenic acid, which binds retinoic acid receptors RAR-beta and RAR-gamma with relative selectivity and may modify gene expression in psoriatic and acne-affected skin.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Seysara
- Covered on 5 commercial plans
- PA (9/12) · Step Therapy (9/12) · Qty limit (9/12)
No coverage data available for Tazorac.
UnitedHealthcare
Seysara
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
No coverage data available for Tazorac.
Humana
Seysara
- Covered on 0 commercial plans
- PA (0/3) · Step Therapy (2/3) · Qty limit (2/3)
No coverage data available for Tazorac.
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Seysara.
No savings programs available for Tazorac.
Compare Other Drugs
Let us handle your prior authsJust enter your patient's info and we'll:
- Verify eligibility with the payer.
- Pull the right PA forms directly from the payer.
- Submit, track & send live updates to your dashboard.
Free to start · HIPAA compliant
Next Steps for Your Patient
SeysaraView full Seysara profile
TazoracView full Tazorac profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.