| Acne Vulgaris
Tazorac vs Absorica
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Tazorac vs Absorica Ld with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsAbsorica Ld has a higher rate of injection site reactions vs Tazorac based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Absorica Ld but not Tazorac, including UnitedHealthcare
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Category
Tazorac
Absorica Ld
At A Glance
Topical
Daily
Retinoid
Oral
Twice daily
Retinoid
Indications
- Psoriasis vulgaris
- Acne Vulgaris
- Acne Vulgaris
Dosing
Psoriasis vulgaris Apply a thin film (2 mg/cm2) of 0.05% cream once daily in the evening to psoriatic lesions only; increase to 0.1% if tolerated and medically indicated.
Acne Vulgaris Apply a thin layer (2 mg/cm2) of 0.1% cream once daily in the evening to affected facial skin areas after gentle cleansing and drying.
Acne Vulgaris ABSORICA: 0.5 to 1 mg/kg/day in two divided doses for 15 to 20 weeks (up to 2 mg/kg/day for severe disease with scarring or trunk involvement); ABSORICA LD: 0.4 to 0.8 mg/kg/day in two divided doses for 15 to 20 weeks (up to 1.6 mg/kg/day for severe disease).
Contraindications
- Pregnancy (retinoids may cause fetal harm)
- Known hypersensitivity to any component of TAZORAC Cream
- Pregnancy
- Hypersensitivity to isotretinoin, Vitamin A (given chemical similarity), or any component of the product
Adverse Reactions
Most common (>=10%) Psoriasis: pruritus, erythema, burning; Acne: desquamation, dry skin, erythema, burning sensation
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Postmarketing Blister, dermatitis, urticaria, skin exfoliation, skin discoloration (hyperpigmentation or hypopigmentation), swelling at or near application sites, pain
Most common Cheilitis, hypertriglyceridemia, dry skin, dry lips, fatigue, headache, epistaxis, arthralgia, back pain, musculoskeletal pain
Serious Embryo-fetal toxicity, psychiatric disorders (including suicidal ideation, depression, psychosis), intracranial hypertension, serious skin reactions, pancreatitis, hepatotoxicity, inflammatory bowel disease, musculoskeletal abnormalities, hearing impairment, hypersensitivity reactions
Pharmacology
Tazarotene is a retinoid prodrug converted by esterase hydrolysis to tazarotenic acid, which binds retinoic acid receptors RAR-beta and RAR-gamma with relative selectivity and may modify gene expression in psoriatic and acne-affected skin.
Isotretinoin is a retinoid that inhibits sebaceous gland function and keratinization; clinical improvement in nodular acne is associated with a reduction in sebum secretion, reflecting reduced sebaceous gland size and inhibition of sebaceous gland differentiation.
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Most Common Insurance
Anthem BCBS
No coverage data available for Tazorac.
Absorica Ld
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (0/12) · Qty limit (0/12)
UnitedHealthcare
No coverage data available for Tazorac.
Absorica Ld
- Covered on 4 commercial plans
- PA (2/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
No coverage data available for Tazorac.
Absorica Ld
- Covered on 0 commercial plans
- PA (0/3) · Step Therapy (0/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Tazorac.
No savings programs available for Absorica Ld.
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TazoracView full Tazorac profile
Absorica LdView full Absorica Ld profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.