| Acne Vulgaris
Tazorac vs Aczone
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Tazorac vs Aczone with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsAczone has a higher rate of injection site reactions vs Tazorac based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Aczone but not Tazorac, including UnitedHealthcare
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Category
Tazorac
Aczone
At A Glance
Topical
Daily
Retinoid
Topical
Daily
Sulfone
Indications
- Psoriasis vulgaris
- Acne Vulgaris
- Acne Vulgaris
Dosing
Psoriasis vulgaris Apply a thin film (2 mg/cm2) of 0.05% cream once daily in the evening to psoriatic lesions only; increase to 0.1% if tolerated and medically indicated.
Acne Vulgaris Apply a thin layer (2 mg/cm2) of 0.1% cream once daily in the evening to affected facial skin areas after gentle cleansing and drying.
Acne Vulgaris Apply approximately a pea-sized amount of ACZONE Gel, 7.5% in a thin layer to the entire face once daily; a thin layer may also be applied to other affected areas once daily.
Contraindications
- Pregnancy (retinoids may cause fetal harm)
- Known hypersensitivity to any component of TAZORAC Cream
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Adverse Reactions
Most common (>=10%) Psoriasis: pruritus, erythema, burning; Acne: desquamation, dry skin, erythema, burning sensation
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Postmarketing Blister, dermatitis, urticaria, skin exfoliation, skin discoloration (hyperpigmentation or hypopigmentation), swelling at or near application sites, pain
Most common (>=0.9%) Application site dryness, application site pruritus
Serious Agranulocytosis, hemolytic anemia, peripheral neuropathy, toxic epidermal necrolysis, erythema multiforme, bullous and exfoliative dermatitis, erythema nodosum, urticaria (reported with oral use of dapsone)
Postmarketing Methemoglobinemia, rash (including erythematous rash, application site rash), swelling of face (including lip swelling, eye swelling)
Pharmacology
Tazarotene is a retinoid prodrug converted by esterase hydrolysis to tazarotenic acid, which binds retinoic acid receptors RAR-beta and RAR-gamma with relative selectivity and may modify gene expression in psoriatic and acne-affected skin.
Dapsone is a sulfone whose mechanism of action in treating acne vulgaris is not known; topical application results in minimal systemic absorption.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
No coverage data available for Tazorac.
Aczone
- Covered on 5 commercial plans
- PA (5/12) · Step Therapy (5/12) · Qty limit (9/12)
UnitedHealthcare
No coverage data available for Tazorac.
Aczone
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (4/8)
Humana
No coverage data available for Tazorac.
Aczone
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Tazorac.
No savings programs available for Aczone.
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TazoracView full Tazorac profile
AczoneView full Aczone profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.