| Acne Vulgaris
Tazorac vs Epiduo Forte
Side-by-side clinical, coverage, and cost comparison for acne vulgaris.Deep comparison between: Tazorac vs Epiduo with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsEpiduo has a higher rate of injection site reactions vs Tazorac based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Epiduo but not Tazorac, including UnitedHealthcare
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Category
Tazorac
Epiduo
At A Glance
Topical
Daily
Retinoid
Topical
Daily
Retinoid + benzoyl peroxide combination
Indications
- Psoriasis vulgaris
- Acne Vulgaris
- Acne Vulgaris
Dosing
Psoriasis vulgaris Apply a thin film (2 mg/cm2) of 0.05% cream once daily in the evening to psoriatic lesions only; increase to 0.1% if tolerated and medically indicated.
Acne Vulgaris Apply a thin layer (2 mg/cm2) of 0.1% cream once daily in the evening to affected facial skin areas after gentle cleansing and drying.
Acne Vulgaris Apply a thin film once daily after washing to affected areas of the face and/or trunk; use a pea-sized amount for each area of the face.
Contraindications
- Pregnancy (retinoids may cause fetal harm)
- Known hypersensitivity to any component of TAZORAC Cream
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Adverse Reactions
Most common (>=10%) Psoriasis: pruritus, erythema, burning; Acne: desquamation, dry skin, erythema, burning sensation
Serious Embryofetal toxicity, photosensitivity and risk of sunburn
Postmarketing Blister, dermatitis, urticaria, skin exfoliation, skin discoloration (hyperpigmentation or hypopigmentation), swelling at or near application sites, pain
Most common (>=1%) Dry skin, contact dermatitis, application site burning, application site irritation, skin irritation
Postmarketing Eyelid edema, sunburn, blister, pain of skin, pruritus, swelling face, conjunctivitis, skin discoloration, rash, eczema, throat tightness, allergic contact dermatitis
Pharmacology
Tazarotene is a retinoid prodrug converted by esterase hydrolysis to tazarotenic acid, which binds retinoic acid receptors RAR-beta and RAR-gamma with relative selectivity and may modify gene expression in psoriatic and acne-affected skin.
Adapalene is a retinoid that modulates cellular differentiation, keratinization, and inflammatory processes; benzoyl peroxide is an oxidizing agent with bactericidal and keratolytic effects.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
No coverage data available for Tazorac.
Epiduo
- Covered on 5 commercial plans
- PA (9/12) · Step Therapy (0/12) · Qty limit (9/12)
UnitedHealthcare
No coverage data available for Tazorac.
Epiduo
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (5/8)
Humana
No coverage data available for Tazorac.
Epiduo
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Tazorac.
No savings programs available for Epiduo.
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TazoracView full Tazorac profile
EpiduoView full Epiduo profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.