| Asthma
Arnuity Ellipta vs Advair Diskus
Side-by-side clinical, coverage, and cost comparison for asthma.Deep comparison between: Arnuity Ellipta vs Advair with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsAdvair has a higher rate of injection site reactions vs Arnuity Ellipta based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Advair but not Arnuity Ellipta, including UnitedHealthcare
Sign up to reveal the full AI analysis
Category
Arnuity Ellipta
Advair
At A Glance
Oral inhalation
Once daily
Inhaled corticosteroid
Oral inhalation
Twice daily
ICS/LABA combination
Indications
- Asthma
- Asthma
- Chronic Obstructive Airway Disease
Dosing
Asthma (>=12 years) 1 actuation of ARNUITY ELLIPTA 100 mcg or 200 mcg once daily by oral inhalation; starting dosage based on prior asthma therapy and disease severity; maximum 200 mcg once daily.
Asthma (5-11 years) 1 actuation of ARNUITY ELLIPTA 50 mcg once daily by oral inhalation.
Asthma 1 inhalation twice daily approximately 12 hours apart; adults and adolescents aged >=12 years may use 100/50, 250/50, or 500/50 strengths (max ADVAIR DISKUS 500/50 twice daily); pediatric patients aged 4 to 11 years use 1 inhalation of ADVAIR DISKUS 100/50 twice daily.
Chronic Obstructive Airway Disease 1 inhalation of ADVAIR DISKUS 250/50 twice daily approximately 12 hours apart.
Contraindications
- Primary treatment of status asthmaticus or other acute episodes of asthma requiring intensive measures
- Severe hypersensitivity to milk proteins or demonstrated hypersensitivity to fluticasone furoate or any excipient
- Primary treatment of status asthmaticus or other acute episodes of asthma or COPD where intensive measures are required
- Severe hypersensitivity to milk proteins or demonstrated hypersensitivity to fluticasone propionate, salmeterol, or any of the excipients
Adverse Reactions
Most common (>=3%) Nasopharyngitis, headache, bronchitis, upper respiratory tract infection, pharyngitis, sinusitis, oral candidiasis, oropharyngeal candidiasis, oropharyngeal pain, toothache, gastroenteritis viral
Serious Hypertension, abscess, breast cancer, traumatic limb amputation, subarachnoid hemorrhage, intervertebral disc protrusion
Postmarketing Anaphylaxis, angioedema, rash, urticaria
Most common (>=3%) Upper respiratory tract infection, pharyngitis, headaches, candidiasis mouth/throat, throat irritation, hoarseness/dysphonia, musculoskeletal pain, viral respiratory infections, nausea and vomiting, bronchitis, sinusitis, dizziness, muscle cramps and spasms
Serious Serious asthma-related events (hospitalizations, intubations, death), pneumonia in patients with COPD, cardiovascular and CNS effects, Candida albicans infection, immunosuppression, hypercorticism and adrenal suppression, reduction in bone mineral density, growth effects in pediatric patients, glaucoma and cataracts
Postmarketing Arrhythmias (including atrial fibrillation, supraventricular tachycardia, ventricular tachycardia), Cushing's syndrome, glaucoma, hyperglycemia, osteoporosis, paradoxical bronchospasm, immediate and delayed hypersensitivity reactions including anaphylaxis, agitation, depression, dysmenorrhea
Pharmacology
Fluticasone furoate is a synthetic trifluorinated corticosteroid with anti-inflammatory activity that binds the human glucocorticoid receptor with high affinity (approximately 29.9 times that of dexamethasone), inhibiting pro-inflammatory transcription factors such as NFkB and mediators involved in asthma pathogenesis.
ADVAIR DISKUS combines fluticasone propionate, a synthetic trifluorinated corticosteroid that suppresses airway inflammation by acting on multiple cell types and mediators, and salmeterol, a selective long-acting beta2-adrenergic agonist (LABA) that relaxes bronchial smooth muscle by stimulating intracellular adenyl cyclase, increasing cyclic AMP levels.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Arnuity Ellipta
- Covered on 5 commercial plans
- PA (9/12) · Step Therapy (5/12) · Qty limit (11/12)
Advair
- Covered on 5 commercial plans
- PA (9/12) · Step Therapy (5/12) · Qty limit (10/12)
UnitedHealthcare
Arnuity Ellipta
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (8/8)
Advair
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Arnuity Ellipta
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (1/3) · Qty limit (3/3)
Advair
- Covered on 0 commercial plans
- PA (2/3) · Step Therapy (2/3) · Qty limit (3/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Arnuity Ellipta.
No savings programs available for Advair.
Compare Other Drugs
Let us handle your prior authsJust enter your patient's info and we'll:
- Verify eligibility with the payer.
- Pull the right PA forms directly from the payer.
- Submit, track & send live updates to your dashboard.
Free to start · HIPAA compliant
Next Steps for Your Patient
Arnuity ElliptaView full Arnuity Ellipta profile
AdvairView full Advair profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.