| Attention deficit hyperactivity disorder
Concerta vs Quillivant XR
Side-by-side clinical, coverage, and cost comparison for attention deficit hyperactivity disorder.Deep comparison between: Concerta vs Quillivant with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsQuillivant has a higher rate of injection site reactions vs Concerta based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Quillivant but not Concerta, including UnitedHealthcare
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Category
Concerta
Quillivant
At A Glance
Oral
Once daily
CNS stimulant
Oral
Daily
CNS stimulant
Indications
- Attention deficit hyperactivity disorder
- Attention deficit hyperactivity disorder
Dosing
Attention deficit hyperactivity disorder 18 mg once daily in the morning (adults may start at 18 or 36 mg); swallow whole; titrate by 18 mg weekly; max 54 mg/day (ages 6-12), 72 mg/day (ages 13-65).
Attention deficit hyperactivity disorder Starting dose 20 mg once daily in the morning for patients 6 years and above; may titrate weekly in increments of 10 mg to 20 mg; daily doses above 60 mg have not been studied and are not recommended.
Contraindications
- Known hypersensitivity to methylphenidate or other components of CONCERTA
- Concomitant use of monoamine oxidase inhibitors (MAOIs), or within 14 days following MAOI discontinuation
- Hypersensitivity to methylphenidate or other components of QUILLIVANT XR
- Concomitant or recent (within 14 days) use of monoamine oxidase inhibitors (MAOIs)
Adverse Reactions
Most common (>=5%) Adults: decreased appetite, headache, dry mouth, nausea, insomnia, anxiety, dizziness, weight decreased, irritability, tachycardia, hyperhidrosis; pediatric patients 6 years and older: upper abdominal pain
Serious Hypersensitivity reactions (angioedema, anaphylaxis), hypertensive crisis with MAOIs, increased blood pressure and heart rate, psychiatric adverse reactions, priapism, peripheral vasculopathy including Raynaud's phenomenon, long-term growth suppression in pediatric patients
Postmarketing Pancytopenia, thrombocytopenia, angina pectoris, bradycardia, supraventricular tachycardia, hepatocellular injury, acute hepatic failure, convulsion, stroke, serotonin syndrome, hallucination, mania, priapism, alopecia, Raynaud's phenomenon, rhabdomyolysis
Most common (>=2%) affect lability, excoriation, initial insomnia, tic, decreased appetite, vomiting, motion sickness, eye pain, rash
Postmarketing pancytopenia, thrombocytopenia, angina pectoris, bradycardia, severe hepatocellular injury, angioedema, anaphylactic reactions, rhabdomyolysis, convulsion, dyskinesia, serotonin syndrome, hallucinations, mania, priapism, alopecia, Raynaud's phenomenon
Pharmacology
Methylphenidate is a CNS stimulant that blocks reuptake of norepinephrine and dopamine into the presynaptic neuron and increases release of these monoamines into the extraneuronal space; its therapeutic mechanism in ADHD is not fully known.
Methylphenidate is a CNS stimulant that blocks reuptake of norepinephrine and dopamine into the presynaptic neuron and increases the release of these monoamines into the extraneuronal space; the mode of therapeutic action in ADHD is not fully known.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Concerta
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (9/12) · Qty limit (10/12)
Quillivant
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (10/12)
UnitedHealthcare
Concerta
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (1/8)
Quillivant
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (1/8)
Humana
Concerta
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (0/3) · Qty limit (3/3)
Quillivant
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (1/3) · Qty limit (3/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Concerta.
No savings programs available for Quillivant.
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.