| Attention deficit hyperactivity disorder
QuilliChew ER vs Quillivant XR
Side-by-side clinical, coverage, and cost comparison for attention deficit hyperactivity disorder.Deep comparison between: Quillichew Er vs Quillivant with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsQuillivant has a higher rate of injection site reactions vs Quillichew Er based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Quillivant but not Quillichew Er, including UnitedHealthcare
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Category
Quillichew Er
Quillivant
At A Glance
Oral
Daily
CNS stimulant
Oral
Daily
CNS stimulant
Indications
- Attention deficit hyperactivity disorder
- Attention deficit hyperactivity disorder
Dosing
Attention deficit hyperactivity disorder Starting dose 20 mg once daily orally in the morning for patients 6 years and above; titrate weekly in increments of 10 mg, 15 mg, or 20 mg; doses above 60 mg/day have not been studied and are not recommended.
Attention deficit hyperactivity disorder Starting dose 20 mg once daily in the morning for patients 6 years and above; may titrate weekly in increments of 10 mg to 20 mg; daily doses above 60 mg have not been studied and are not recommended.
Contraindications
- Hypersensitivity to methylphenidate or other components of QuilliChew ER
- Concomitant use with monoamine oxidase inhibitors (MAOIs) or within 14 days following MAOI discontinuation
- Hypersensitivity to methylphenidate or other components of QUILLIVANT XR
- Concomitant or recent (within 14 days) use of monoamine oxidase inhibitors (MAOIs)
Adverse Reactions
Most common (>=2%) Decreased appetite, aggression, emotional poverty, nausea, headache, weight decreased
Postmarketing Pancytopenia, thrombocytopenia, angina pectoris, severe hepatocellular injury, angioedema, anaphylactic reactions, convulsion, dyskinesia, serotonin syndrome, hallucination, mania, priapism, rhabdomyolysis, Raynaud's phenomenon
Most common (>=2%) affect lability, excoriation, initial insomnia, tic, decreased appetite, vomiting, motion sickness, eye pain, rash
Postmarketing pancytopenia, thrombocytopenia, angina pectoris, bradycardia, severe hepatocellular injury, angioedema, anaphylactic reactions, rhabdomyolysis, convulsion, dyskinesia, serotonin syndrome, hallucinations, mania, priapism, alopecia, Raynaud's phenomenon
Pharmacology
Methylphenidate is a CNS stimulant that blocks the reuptake of norepinephrine and dopamine into the presynaptic neuron and increases the release of these monoamines into the extraneuronal space; the d-isomer is more pharmacologically active than the l-isomer.
Methylphenidate is a CNS stimulant that blocks reuptake of norepinephrine and dopamine into the presynaptic neuron and increases the release of these monoamines into the extraneuronal space; the mode of therapeutic action in ADHD is not fully known.
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Most Common Insurance
Anthem BCBS
Quillichew Er
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (10/12)
Quillivant
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (10/12)
UnitedHealthcare
Quillichew Er
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Quillivant
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (1/8)
Humana
Quillichew Er
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (1/3) · Qty limit (3/3)
Quillivant
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (1/3) · Qty limit (3/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Quillichew Er.
No savings programs available for Quillivant.
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.