| Diabetes Mellitus, Non-Insulin-Dependent
Basaglar vs Brenzavvy
Side-by-side clinical, coverage, and cost comparison for diabetes mellitus, non-insulin-dependent.Deep comparison between: Basaglar vs Brenzavvy with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsBrenzavvy has a higher rate of injection site reactions vs Basaglar based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Brenzavvy but not Basaglar, including UnitedHealthcare
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Category
Basaglar
Brenzavvy
At A Glance
SC injection
Once daily
Long-acting insulin analog
Oral
Daily
SGLT2 inhibitor
Indications
- Diabetes Mellitus, Non-Insulin-Dependent
- Diabetes Mellitus, Non-Insulin-Dependent
Dosing
Type 1 Diabetes Mellitus Approximately one-third of total daily insulin requirements SC once daily; short- or rapid-acting pre-meal insulin covers the remainder.
Diabetes Mellitus, Non-Insulin-Dependent 0.2 units/kg or up to 10 units SC once daily.
Diabetes Mellitus, Non-Insulin-Dependent 20 mg orally once daily in the morning, with or without food; do not crush or chew the tablet; withhold for at least 3 days prior to major surgery or procedures associated with prolonged fasting.
Contraindications
- Episodes of hypoglycemia
- Hypersensitivity to insulin glargine or any excipient in BASAGLAR
- Hypersensitivity to bexagliflozin or any excipient in BRENZAVVY
Adverse Reactions
Most common (>=5%) Infection, nasopharyngitis, upper respiratory tract infection
Serious Severe hypoglycemia, anaphylaxis, peripheral edema, lipodystrophy, localized cutaneous amyloidosis
Postmarketing Medication errors (accidental administration of rapid-acting insulin instead of insulin glargine), localized cutaneous amyloidosis, hyperglycemia or hypoglycemia associated with injection site changes
Most common (>=2%) Increased urination, urinary tract infection, female genital mycotic infections, thirst, vaginal pruritus, male genital mycotic infection, hypoglycemia
Serious Diabetic ketoacidosis, lower limb amputation, volume depletion, urosepsis, pyelonephritis, necrotizing fasciitis of the perineum, sepsis, fractures
Pharmacology
Insulin glargine is a long-acting human insulin analog that lowers blood glucose by stimulating peripheral glucose uptake in skeletal muscle and fat and inhibiting hepatic glucose production, providing sustained glucose-lowering activity over 24 hours with no pronounced peak.
Bexagliflozin is an SGLT2 inhibitor that blocks renal reabsorption of filtered glucose in the proximal tubule, lowering the renal threshold for glucose and increasing urinary glucose excretion to reduce blood glucose in adults with type 2 diabetes mellitus.
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Most Common Insurance
Anthem BCBS
Basaglar
- Covered on 5 commercial plans
- PA (1/12) · Step Therapy (6/12) · Qty limit (0/12)
Brenzavvy
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (5/12) · Qty limit (9/12)
UnitedHealthcare
Basaglar
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Brenzavvy
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Basaglar
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (0/3)
Brenzavvy
- Covered on 0 commercial plans
- PA (0/3) · Step Therapy (0/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Basaglar.
No savings programs available for Brenzavvy.
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BasaglarView full Basaglar profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.