| Diabetes Mellitus
Apidra vs Rezgovlar
Side-by-side clinical, coverage, and cost comparison for diabetes mellitus.Deep comparison between: Apidra vs Rezvoglar with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsRezvoglar has a higher rate of injection site reactions vs Apidra based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Rezvoglar but not Apidra, including UnitedHealthcare
Sign up to reveal the full AI analysis
Category
Apidra
Rezvoglar
At A Glance
SC injection
With meals
Rapid-acting insulin analog
SC injection
Once daily
Long-acting insulin analog
Indications
- Diabetes Mellitus
- Diabetes Mellitus
Dosing
Diabetes Mellitus Inject SC within 15 minutes before a meal or within 20 minutes after starting a meal into the abdomen, thigh, or upper arm; generally use with an intermediate or long-acting insulin.
Continuous Subcutaneous Infusion (Insulin Pump) Administer by CSII using an insulin pump per manufacturer instructions; change reservoir at least every 48 hours; do not dilute or mix with other insulins in the pump.
Intravenous Administration Administer only under medical supervision; dilute to 0.05-1 unit/mL in 0.9% sodium chloride injection using polyvinyl chloride infusion bags.
Diabetes Mellitus, Type 1 Approximately one-third of total daily insulin requirements SC once daily at the same time every day; use short-acting premeal insulin for the remainder.
Diabetes Mellitus, Type 2 0.2 units/kg or up to 10 units SC once daily in insulin-naive patients, adjusted based on metabolic needs and blood glucose monitoring results.
Contraindications
- During episodes of hypoglycemia
- Known hypersensitivity to insulin glulisine or any of the excipients in APIDRA
- Episodes of hypoglycemia
- Hypersensitivity to insulin glargine products or any excipient in REZVOGLAR
Adverse Reactions
Most common (>=5%) Nasopharyngitis, hypoglycemia, upper respiratory tract infection, influenza, peripheral edema, arthralgia, headache
Serious Severe hypoglycemia, anaphylaxis and generalized allergic reactions, hypokalemia, lipodystrophy, worsening of diabetic retinopathy, acute painful peripheral neuropathy
Postmarketing Medication errors with long-acting insulins, localized cutaneous amyloidosis, hyperglycemia and hypoglycemia associated with injection into amyloidosis sites
Most common (>=5%) Upper respiratory tract infection, infection, accidental injury, headache, retinal vascular disorder
Serious Severe hypoglycemia, anaphylaxis, angioedema, bronchospasm, hypotension, shock, hypokalemia, lipodystrophy
Postmarketing Localized cutaneous amyloidosis, medication errors with inadvertent insulin substitution, hyperglycemia or hypoglycemia related to injections into amyloidosis-affected sites
Pharmacology
Rapid-acting human insulin analog; lowers blood glucose by stimulating peripheral glucose uptake in skeletal muscle and fat and inhibiting hepatic glucose production, with more rapid onset and shorter duration of activity than regular human insulin when given subcutaneously.
Long-acting human insulin analog; regulates glucose metabolism by stimulating peripheral glucose uptake in skeletal muscle and fat and inhibiting hepatic glucose production, lipolysis, and proteolysis while enhancing protein synthesis.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Apidra
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
Rezvoglar
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (5/12) · Qty limit (9/12)
UnitedHealthcare
Apidra
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (1/8) · Qty limit (0/8)
Rezvoglar
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (1/8) · Qty limit (2/8)
Humana
Apidra
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (3/3) · Qty limit (0/3)
Rezvoglar
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (2/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Apidra.
No savings programs available for Rezvoglar.
Compare Other Drugs
Let us handle your prior authsJust enter your patient's info and we'll:
- Verify eligibility with the payer.
- Pull the right PA forms directly from the payer.
- Submit, track & send live updates to your dashboard.
Free to start · HIPAA compliant
Next Steps for Your Patient
ApidraView full Apidra profile
RezvoglarView full Rezvoglar profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.