| Diabetes Mellitus
Novolog vs Novolog 70/30
Side-by-side clinical, coverage, and cost comparison for diabetes mellitus.Deep comparison between: Insulin Diluting Medium For Novolog vs Novolog Mix 70/30 with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsNovolog Mix 70/30 has a higher rate of injection site reactions vs Insulin Diluting Medium For Novolog based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Novolog Mix 70/30 but not Insulin Diluting Medium For Novolog, including UnitedHealthcare
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Category
Insulin Diluting Medium For Novolog
Novolog Mix 70/30
At A Glance
SC injection
Pre-meal
Rapid-acting insulin analog
SC injection
Twice daily
Insulin analog
Indications
- Diabetes Mellitus
- Diabetes Mellitus
Dosing
Diabetes Mellitus Inject SC within 5-10 minutes before a meal into the abdominal area, thigh, buttocks, or upper arm; generally used with an intermediate- or long-acting insulin; may also be administered via continuous SC infusion pump or diluted to 0.05-1 unit/mL for IV infusion; individualize dose based on metabolic needs and blood glucose monitoring results.
Diabetes Mellitus Inject subcutaneously in the abdominal region, buttocks, thigh, or upper arm twice daily within 15 minutes before meal initiation (or after meal initiation for type 2 patients); individualize dose based on metabolic needs, blood glucose monitoring results, and glycemic control goal.
Contraindications
- Episodes of hypoglycemia
- Hypersensitivity to NOVOLOG or one of its excipients
- Episodes of hypoglycemia
- Hypersensitivity to Novolog Mix 70/30 or one of its excipients
Adverse Reactions
Most common (>=5%) Headache, accidental injury, nausea, diarrhea (type 1 diabetes); hyporeflexia, onychomycosis, sensory disturbance, urinary tract infection, chest pain, skin disorder, abdominal pain, sinusitis (type 2 diabetes)
Serious Severe hypoglycemia, generalized allergy/anaphylaxis, hypokalemia, lipodystrophy, peripheral edema
Postmarketing Localized cutaneous amyloidosis at injection site, medication errors with insulin substitution, hyperglycemia or hypoglycemia associated with amyloidosis-related injection site changes
Most common (>=5%) Hypoglycemia, headache, influenza-like symptoms, dyspepsia, back pain, diarrhea, pharyngitis, rhinitis, skeletal pain, upper respiratory tract infection, neuropathy, abdominal pain
Serious Severe hypoglycemia requiring assistance or parenteral glucose/glucagon, anaphylaxis, lipodystrophy, localized cutaneous amyloidosis
Postmarketing Localized cutaneous amyloidosis at injection site, hyperglycemia with repeated injections into areas of amyloidosis, hypoglycemia with sudden change to unaffected injection site, medication errors due to accidental substitution
Pharmacology
Rapid-acting human insulin analog; regulates glucose metabolism by stimulating peripheral glucose uptake in skeletal muscle and fat and inhibiting hepatic glucose production, with peak glucose-lowering effect 1-3 hours after SC injection and duration of action 3-5 hours.
Biphasic insulin analog consisting of 70% insulin aspart protamine (prolonged absorption) and 30% soluble insulin aspart (rapid absorption); lowers blood glucose by stimulating peripheral glucose uptake in skeletal muscle and fat and by inhibiting hepatic glucose production.
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Most Common Insurance
Anthem BCBS
Insulin Diluting Medium For Novolog
- Covered on 5 commercial plans
- PA (5/12) · Step Therapy (5/12) · Qty limit (0/12)
Novolog Mix 70/30
- Covered on 5 commercial plans
- PA (5/12) · Step Therapy (5/12) · Qty limit (0/12)
UnitedHealthcare
Insulin Diluting Medium For Novolog
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Novolog Mix 70/30
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (2/8)
Humana
Insulin Diluting Medium For Novolog
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (0/3)
Novolog Mix 70/30
- Covered on 0 commercial plans
- PA (0/3) · Step Therapy (0/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Insulin Diluting Medium For Novolog.
No savings programs available for Novolog Mix 70/30.
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.