| Diabetes Mellitus
Lantus vs Rezgovlar
Side-by-side clinical, coverage, and cost comparison for diabetes mellitus.Deep comparison between: Lantus Solostar vs Rezvoglar with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsRezvoglar has a higher rate of injection site reactions vs Lantus Solostar based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Rezvoglar but not Lantus Solostar, including UnitedHealthcare
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Category
Lantus Solostar
Rezvoglar
At A Glance
SC injection
Once daily
Long-acting insulin analog
SC injection
Once daily
Long-acting insulin analog
Indications
- Diabetes Mellitus
- Diabetes Mellitus
Dosing
Diabetes Mellitus, Type 1 Approximately one-third of total daily insulin requirements SC once daily at the same time each day; use short-acting, premeal insulin to satisfy the remainder.
Diabetes Mellitus, Type 2 0.2 units/kg or up to 10 units SC once daily for insulin-naive patients; adjust based on metabolic needs and glucose monitoring results.
Diabetes Mellitus, Type 1 Approximately one-third of total daily insulin requirements SC once daily at the same time every day; use short-acting premeal insulin for the remainder.
Diabetes Mellitus, Type 2 0.2 units/kg or up to 10 units SC once daily in insulin-naive patients, adjusted based on metabolic needs and blood glucose monitoring results.
Contraindications
- During episodes of hypoglycemia
- Hypersensitivity to insulin glargine or any excipient in LANTUS
- Episodes of hypoglycemia
- Hypersensitivity to insulin glargine products or any excipient in REZVOGLAR
Adverse Reactions
Most common (>=5%) Upper respiratory tract infection, infection (body system unspecified), accidental injury, headache, peripheral edema, retinal vascular disorder, injection site reactions (redness, pain, itching, urticaria, edema, inflammation)
Serious Severe hypoglycemia, systemic hypersensitivity reactions (anaphylaxis, angioedema, bronchospasm, hypotension, shock), hypokalemia, lipodystrophy, weight gain
Postmarketing Medication errors with rapid-acting insulins accidentally administered instead of LANTUS, localized cutaneous amyloidosis at injection site
Most common (>=5%) Upper respiratory tract infection, infection, accidental injury, headache, retinal vascular disorder
Serious Severe hypoglycemia, anaphylaxis, angioedema, bronchospasm, hypotension, shock, hypokalemia, lipodystrophy
Postmarketing Localized cutaneous amyloidosis, medication errors with inadvertent insulin substitution, hyperglycemia or hypoglycemia related to injections into amyloidosis-affected sites
Pharmacology
Insulin glargine is a long-acting human insulin analog that regulates glucose metabolism by stimulating peripheral glucose uptake in skeletal muscle and fat and inhibiting hepatic glucose production, providing a relatively constant concentration/time profile over 24 hours with no pronounced peak after subcutaneous injection.
Long-acting human insulin analog; regulates glucose metabolism by stimulating peripheral glucose uptake in skeletal muscle and fat and inhibiting hepatic glucose production, lipolysis, and proteolysis while enhancing protein synthesis.
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Most Common Insurance
Anthem BCBS
Lantus Solostar
- Covered on 5 commercial plans
- PA (1/12) · Step Therapy (6/12) · Qty limit (0/12)
Rezvoglar
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (5/12) · Qty limit (9/12)
UnitedHealthcare
Lantus Solostar
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Rezvoglar
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (1/8) · Qty limit (2/8)
Humana
Lantus Solostar
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (0/3)
Rezvoglar
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (2/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Lantus Solostar.
No savings programs available for Rezvoglar.
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Lantus SolostarView full Lantus Solostar profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.