| Diabetes Mellitus

Rezgovlar vs Toujeo

Side-by-side clinical, coverage, and cost comparison for diabetes mellitus.
Deep comparison between: Rezvoglar vs Toujeo with Prescriber.AI
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Safety signalsToujeo has a higher rate of injection site reactions vs Rezvoglar based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Toujeo but not Rezvoglar, including UnitedHealthcare
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Rezvoglar
Toujeo
At A Glance
SC injection
Once daily
Long-acting insulin analog
SC injection
Once daily
Long-acting insulin analog
Indications
  • Diabetes Mellitus
  • Diabetes Mellitus
Dosing
Diabetes Mellitus, Type 1 Approximately one-third of total daily insulin requirements SC once daily at the same time every day; use short-acting premeal insulin for the remainder.
Diabetes Mellitus, Type 2 0.2 units/kg or up to 10 units SC once daily in insulin-naive patients, adjusted based on metabolic needs and blood glucose monitoring results.
Diabetes Mellitus, Type 1 (insulin-naive) Approximately one-third to one-half of total daily insulin dose SC once daily; remainder given as short-acting insulin divided between daily meals.
Diabetes Mellitus, Type 2 (insulin-naive) 0.2 units/kg SC once daily.
Switching from once-daily long/intermediate-acting insulin Start at same unit dose as prior once-daily long-acting insulin SC once daily; monitor glucose closely during initial weeks.
Switching from twice-daily long/intermediate-acting insulin Start at 80% of total daily NPH or insulin detemir twice-daily dosage SC once daily; monitor glucose frequently.
Contraindications
  • Episodes of hypoglycemia
  • Hypersensitivity to insulin glargine products or any excipient in REZVOGLAR
  • Active hypoglycemia episode
  • Hypersensitivity to insulin glargine or any excipient in Toujeo
Adverse Reactions
Most common (>=5%) Upper respiratory tract infection, infection, accidental injury, headache, retinal vascular disorder
Serious Severe hypoglycemia, anaphylaxis, angioedema, bronchospasm, hypotension, shock, hypokalemia, lipodystrophy
Postmarketing Localized cutaneous amyloidosis, medication errors with inadvertent insulin substitution, hyperglycemia or hypoglycemia related to injections into amyloidosis-affected sites
Most common (>=5%) nasopharyngitis, upper respiratory tract infection, hypoglycemia
Serious severe hypoglycemia, anaphylaxis, peripheral edema, lipodystrophy, hypokalemia
Postmarketing localized cutaneous amyloidosis at injection site, hyperglycemia or hypoglycemia associated with injections into or away from amyloidosis areas
Pharmacology
Long-acting human insulin analog; regulates glucose metabolism by stimulating peripheral glucose uptake in skeletal muscle and fat and inhibiting hepatic glucose production, lipolysis, and proteolysis while enhancing protein synthesis.
Long-acting insulin analog; regulates glucose metabolism by stimulating peripheral glucose uptake in skeletal muscle and fat, inhibiting hepatic glucose production, inhibiting lipolysis and proteolysis, and enhancing protein synthesis.
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Most Common Insurance
Anthem BCBS
Rezvoglar
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (5/12) · Qty limit (9/12)
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Toujeo
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (5/12) · Qty limit (9/12)
View full coverage details ›
UnitedHealthcare
Rezvoglar
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (1/8) · Qty limit (2/8)
View full coverage details ›
Toujeo
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (1/8) · Qty limit (0/8)
View full coverage details ›
Humana
Rezvoglar
  • Covered on 0 commercial plans
  • PA (3/3) · Step Therapy (2/3) · Qty limit (0/3)
View full coverage details ›
Toujeo
  • Covered on 0 commercial plans
  • PA (2/3) · Step Therapy (2/3) · Qty limit (0/3)
View full coverage details ›
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Rezvoglar.
No savings programs available for Toujeo.
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RezvoglarView full Rezvoglar profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.