| Glaucoma, Open-Angle
Rhopressa vs Travatan Z
Side-by-side clinical, coverage, and cost comparison for glaucoma, open-angle.Deep comparison between: Rhopressa vs Travatan Z with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsTravatan Z has a higher rate of injection site reactions vs Rhopressa based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Travatan Z but not Rhopressa, including UnitedHealthcare
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Category
Rhopressa
Travatan Z
At A Glance
Ophthalmic (eye drop)
Once daily (evening)
Rho kinase inhibitor
Ophthalmic
Once daily (evening)
Prostaglandin analog
Indications
- Glaucoma, Open-Angle
- Ocular Hypertension
- Glaucoma, Open-Angle
- Ocular Hypertension
Dosing
Glaucoma, Open-Angle, Ocular Hypertension One drop in the affected eye(s) once daily in the evening; when used concomitantly with other topical ophthalmic products to lower IOP, administer each product at least 5 minutes apart.
Glaucoma, Open-Angle, Ocular Hypertension One drop in the affected eye(s) once daily in the evening; do not administer more than once daily. If used with other topical ophthalmic drugs, administer at least 5 minutes apart.
Contraindications
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Adverse Reactions
Most common (>=20%) Conjunctival hyperemia, corneal verticillata, instillation site pain, conjunctival hemorrhage
Common (5-10%) Instillation site erythema, corneal staining, blurred vision, increased lacrimation, erythema of eyelid, reduced visual acuity
Postmarketing Epithelial corneal edema in patients with pre-existing corneal stromal edema or following ocular procedures affecting corneal endothelial function
Most common (30% to 50%) Ocular hyperemia (conjunctival hyperemia)
Ocular (5% to 10%) Decreased visual acuity, eye discomfort, foreign body sensation, pain, pruritus
Postmarketing Arrhythmia, vomiting, epistaxis, tachycardia, insomnia, periorbital and lid changes including deepening of the eyelid sulcus
Pharmacology
Netarsudil is a rho kinase inhibitor believed to reduce intraocular pressure by increasing the outflow of aqueous humor through the trabecular meshwork; the exact mechanism is unknown.
Travoprost free acid is a selective FP prostanoid receptor agonist (prostaglandin analog) believed to reduce intraocular pressure by increasing uveoscleral outflow; the exact mechanism is unknown.
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Most Common Insurance
Anthem BCBS
Rhopressa
- Covered on 5 commercial plans
- PA (5/12) · Step Therapy (6/12) · Qty limit (9/12)
Travatan Z
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (0/12) · Qty limit (9/12)
UnitedHealthcare
Rhopressa
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (2/8) · Qty limit (4/8)
Travatan Z
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Rhopressa
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (2/3) · Qty limit (1/3)
Travatan Z
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (3/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Rhopressa.
No savings programs available for Travatan Z.
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RhopressaView full Rhopressa profile
Travatan ZView full Travatan Z profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.