| Glaucoma, Open-Angle
Travatan Z vs Xalatan
Side-by-side clinical, coverage, and cost comparison for glaucoma, open-angle.Deep comparison between: Travatan Z vs Xalatan with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsXalatan has a higher rate of injection site reactions vs Travatan Z based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Xalatan but not Travatan Z, including UnitedHealthcare
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Category
Travatan Z
Xalatan
At A Glance
Ophthalmic
Once daily (evening)
Prostaglandin analog
Ophthalmic
Once daily
Prostaglandin F2-alpha analogue
Indications
- Glaucoma, Open-Angle
- Ocular Hypertension
- Glaucoma, Open-Angle
- Ocular Hypertension
Dosing
Glaucoma, Open-Angle, Ocular Hypertension One drop in the affected eye(s) once daily in the evening; do not administer more than once daily. If used with other topical ophthalmic drugs, administer at least 5 minutes apart.
Glaucoma, Open-Angle, Ocular Hypertension One drop in the affected eye(s) once daily in the evening; do not exceed once daily dosing.
Contraindications
—
- Known hypersensitivity to latanoprost, benzalkonium chloride, or any other ingredients in this product
Adverse Reactions
Most common (30% to 50%) Ocular hyperemia (conjunctival hyperemia)
Ocular (5% to 10%) Decreased visual acuity, eye discomfort, foreign body sensation, pain, pruritus
Postmarketing Arrhythmia, vomiting, epistaxis, tachycardia, insomnia, periorbital and lid changes including deepening of the eyelid sulcus
Most common (5-15%) Foreign body sensation, punctate keratitis, stinging, conjunctival hyperemia, blurred vision, itching, burning, increased pigmentation of the iris
Serious Iris pigmentation changes, eyelid skin darkening, eyelash changes, intraocular inflammation (iritis/uveitis), macular edema including cystoid macular edema
Postmarketing Dizziness, headache, toxic epidermal necrolysis, keratitis, corneal edema and erosions, trichiasis, iris cyst, conjunctivitis, pseudopemphigoid of the ocular conjunctiva, asthma, dyspnea, nausea, vomiting, pruritis, herpes keratitis, angina, palpitations, chest pain
Pharmacology
Travoprost free acid is a selective FP prostanoid receptor agonist (prostaglandin analog) believed to reduce intraocular pressure by increasing uveoscleral outflow; the exact mechanism is unknown.
Latanoprost is a prostaglandin F2-alpha analogue that reduces intraocular pressure by increasing uveoscleral outflow of aqueous humor.
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Most Common Insurance
Anthem BCBS
Travatan Z
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (0/12) · Qty limit (9/12)
Xalatan
- Covered on 5 commercial plans
- PA (0/12) · Step Therapy (0/12) · Qty limit (9/12)
UnitedHealthcare
Travatan Z
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Xalatan
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Travatan Z
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (3/3) · Qty limit (2/3)
Xalatan
- Covered on 0 commercial plans
- PA (0/3) · Step Therapy (0/3) · Qty limit (3/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Travatan Z.
No savings programs available for Xalatan.
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Travatan ZView full Travatan Z profile
XalatanView full Xalatan profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.