| Hypertensive disease
Katerzia vs Tribenzor
Side-by-side clinical, coverage, and cost comparison for hypertensive disease.Deep comparison between: Katerzia vs Tribenzor with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsTribenzor has a higher rate of injection site reactions vs Katerzia based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Tribenzor but not Katerzia, including UnitedHealthcare
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Category
Katerzia
Tribenzor
At A Glance
Oral
Daily
Calcium channel blocker
Oral
Daily
ARB / CCB / thiazide diuretic
Indications
- Hypertensive disease
- Stable angina
- Angina Pectoris, Variant
- Coronary Artery Disease
- Hypertensive disease
Dosing
Hypertensive disease (adults) 5 mg orally once daily (max 10 mg); start 2.5 mg in small, fragile, elderly patients, or those with hepatic insufficiency.
Hypertensive disease (pediatric, ages 6-17) 2.5-5 mg orally once daily; doses >5 mg have not been studied in pediatric patients.
Stable angina, Angina Pectoris, Variant 5-10 mg orally once daily; lower dose suggested in elderly and patients with hepatic insufficiency; most patients require 10 mg.
Coronary Artery Disease 5-10 mg orally once daily; majority of patients required 10 mg in clinical studies.
Hypertensive disease Once daily; dosage may be increased in 2-week intervals as needed; maximum recommended dose is 40/10/25 mg; dose selection should be individualized based on previous therapy.
Contraindications
- Known sensitivity to amlodipine
- Anuria
- Hypersensitivity to any component of Tribenzor or to other sulfonamide-derived drugs
- Co-administration of aliskiren in patients with diabetes
Adverse Reactions
Most common (>1%) edema, dizziness, flushing, palpitation, fatigue, nausea, abdominal pain, somnolence
Postmarketing gynecomastia, jaundice, hepatic enzyme elevations, extrapyramidal disorder
Most common (>=2%) Dizziness, peripheral edema, headache, fatigue, nasopharyngitis, muscle spasms, nausea, upper respiratory tract infection, diarrhea, urinary tract infection, joint swelling
Postmarketing Angioedema, anaphylactic reactions, rhabdomyolysis, acute renal failure, sprue-like enteropathy, hyperkalemia, alopecia, pruritus, urticaria, gynecomastia, jaundice, hepatic enzyme elevations, extrapyramidal disorder, non-melanoma skin cancer (hydrochlorothiazide)
Pharmacology
Amlodipine is a dihydropyridine calcium channel blocker that inhibits transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle, causing peripheral arterial vasodilation, reduction in peripheral vascular resistance, and reduction in blood pressure.
Triple-combination antihypertensive; olmesartan medoxomil selectively blocks angiotensin II AT1 receptors in vascular smooth muscle, amlodipine inhibits transmembrane calcium ion influx into vascular and cardiac smooth muscle, and hydrochlorothiazide promotes renal excretion of sodium and chloride to reduce intravascular volume.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Katerzia
- Covered on 5 commercial plans
- PA (6/12) · Step Therapy (1/12) · Qty limit (8/12)
Tribenzor
- Covered on 5 commercial plans
- PA (4/12) · Step Therapy (0/12) · Qty limit (11/12)
UnitedHealthcare
Katerzia
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Tribenzor
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (2/8)
Humana
Katerzia
- Covered on 0 commercial plans
- PA (0/3) · Step Therapy (2/3) · Qty limit (2/3)
Tribenzor
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Katerzia.
No savings programs available for Tribenzor.
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KaterziaView full Katerzia profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.