| Ocular Hypertension
Travatan Z vs Durysta
Side-by-side clinical, coverage, and cost comparison for ocular hypertension.Deep comparison between: Travatan Z vs Durysta with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsDurysta has a higher rate of injection site reactions vs Travatan Z based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Durysta but not Travatan Z, including UnitedHealthcare
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Category
Travatan Z
Durysta
At A Glance
Ophthalmic
Once daily (evening)
Prostaglandin analog
Intracameral implant
Single dose
Prostaglandin analog
Indications
- Glaucoma, Open-Angle
- Ocular Hypertension
- Glaucoma, Open-Angle
- Ocular Hypertension
Dosing
Glaucoma, Open-Angle, Ocular Hypertension One drop in the affected eye(s) once daily in the evening; do not administer more than once daily. If used with other topical ophthalmic drugs, administer at least 5 minutes apart.
Glaucoma, Open-Angle, Ocular Hypertension Single biodegradable intracameral implant (10 mcg bimatoprost) administered once into the anterior chamber under aseptic conditions; do not readminister to a previously treated eye.
Contraindications
—
- Active or suspected ocular or periocular infections
- Corneal endothelial cell dystrophy (e.g., Fuchs' Dystrophy)
- Prior corneal transplantation or endothelial cell transplants (e.g., DSAEK)
- Absent or ruptured posterior lens capsule (risk of implant migration into the posterior segment)
- Hypersensitivity to bimatoprost or any other component of the product
Adverse Reactions
Most common (30% to 50%) Ocular hyperemia (conjunctival hyperemia)
Ocular (5% to 10%) Decreased visual acuity, eye discomfort, foreign body sensation, pain, pruritus
Postmarketing Arrhythmia, vomiting, epistaxis, tachycardia, insomnia, periorbital and lid changes including deepening of the eyelid sulcus
Most common (>=5%) Conjunctival hyperemia (27%), foreign body sensation, eye pain, photophobia, conjunctival hemorrhage, dry eye, eye irritation, increased IOP, corneal endothelial cell loss, blurred vision, iritis, headache
Serious Implant migration, hypersensitivity, corneal adverse reactions, macular edema, intraocular inflammation, pigmentation, endophthalmitis
Postmarketing Endophthalmitis
Pharmacology
Travoprost free acid is a selective FP prostanoid receptor agonist (prostaglandin analog) believed to reduce intraocular pressure by increasing uveoscleral outflow; the exact mechanism is unknown.
Bimatoprost is a prostaglandin analog with ocular hypotensive activity that lowers IOP by increasing aqueous humor outflow through both the trabecular meshwork (conventional) and uveoscleral (unconventional) routes.
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Most Common Insurance
Anthem BCBS
Travatan Z
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (0/12) · Qty limit (9/12)
Durysta
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
UnitedHealthcare
Travatan Z
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Durysta
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Travatan Z
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (3/3) · Qty limit (2/3)
Durysta
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (0/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Travatan Z.
$0/fillfill
Durysta CoPay Assistance ProgramCommercial or private insurance
Medicare, Medicaid, VA, TRICARE
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Travatan ZView full Travatan Z profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.