| Psoriasis vulgaris

Enstilar vs Sorilux

Side-by-side clinical, coverage, and cost comparison for psoriasis vulgaris.
Deep comparison between: Enstilar vs Sorilux with Prescriber.AI
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Safety signalsSorilux has a higher rate of injection site reactions vs Enstilar based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Sorilux but not Enstilar, including UnitedHealthcare
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Enstilar
Sorilux
At A Glance
Topical
Once daily
Vitamin D3 analog + corticosteroid
Topical
Twice daily
Synthetic vitamin D3 analog
Indications
  • Psoriasis vulgaris
  • Psoriasis vulgaris
Dosing
Psoriasis vulgaris Apply to affected areas once daily for up to 4 weeks; maximum dose not to exceed 60 g every 4 days; rub in gently; do not use with occlusive dressings, on the face, groin, or axillae, or if skin atrophy is present at the treatment site.
Psoriasis vulgaris Apply a thin layer twice daily to affected areas and rub in gently and completely; avoid contact with the face and eyes.
Contraindications
  • Known hypercalcemia
Adverse Reactions
Postmarketing Application site burning, atrophy, striae, telangiectasia, dryness, perioral dermatitis, secondary infection, miliaria, cataracts, glaucoma, increased intraocular pressure.
Most common (>=1%) Application site erythema, application site pain
Postmarketing Application site vesicles
Pharmacology
Enstilar Foam combines calcipotriene hydrate, a synthetic vitamin D3 analog, and betamethasone dipropionate, a synthetic corticosteroid; exact mechanisms of action in the treatment of plaque psoriasis are unknown.
Calcipotriene is a synthetic vitamin D3 analog with similar receptor binding affinity as natural vitamin D3; the exact mechanism contributing to clinical efficacy in psoriasis is unknown.
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Most Common Insurance
Anthem BCBS
Enstilar
  • Covered on 5 commercial plans
  • PA (6/12) · Step Therapy (10/12) · Qty limit (9/12)
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Sorilux
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (6/12) · Qty limit (9/12)
View full coverage details ›
UnitedHealthcare
Enstilar
  • Covered on 4 commercial plans
  • PA (1/8) · Step Therapy (0/8) · Qty limit (3/8)
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Sorilux
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
View full coverage details ›
Humana
Enstilar
  • Covered on 0 commercial plans
  • PA (3/3) · Step Therapy (3/3) · Qty limit (2/3)
View full coverage details ›
Sorilux
  • Covered on 0 commercial plans
  • PA (1/3) · Step Therapy (2/3) · Qty limit (2/3)
View full coverage details ›
Coverage data sourced from MMIT. Updated monthly.
Savings
$30/fillfill
Leo Copay Savings Card: Enstilar
Commercial or private insurance
Medicare, Medicaid, VA, TRICARE
No savings programs available for Sorilux.
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EnstilarView full Enstilar profile
SoriluxView full Sorilux profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.